ID A0A2G2X288_CAPBA Unreviewed; 840 AA.
AC A0A2G2X288;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=CQW23_06069 {ECO:0000313|EMBL:PHT51607.1};
OS Capsicum baccatum (Peruvian pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=33114 {ECO:0000313|EMBL:PHT51607.1, ECO:0000313|Proteomes:UP000224567};
RN [1] {ECO:0000313|EMBL:PHT51607.1, ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RC TISSUE=Leaf {ECO:0000313|EMBL:PHT51607.1};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
RN [2] {ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RA Kim S., Park J., Yeom S.-I., Kim Y.-M., Seo E., Kim K.-T., Kim M.-S.,
RA Lee J.M., Cheong K., Shin H.-S., Kim S.-B., Han K., Lee J., Park M.,
RA Lee H.-A., Lee H.-Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E.,
RA Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.-C., Kwon J.-K.,
RA Lee H.-Y., Koo N., Hong Y., Kim R.W., Kang W.-H., Huh J.H., Kang B.-C.,
RA Yang T.-J., Lee Y.-H., Bennetzen J.L., Choi D.;
RT "Multiple reference genome sequences of hot pepper reveal the massive
RT evolution of plant disease resistance genes by retroduplication.";
RL J. Anim. Genet. bioRxivorg:115410-115410(2017).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT51607.1}.
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DR EMBL; MLFT02000003; PHT51607.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G2X288; -.
DR STRING; 33114.A0A2G2X288; -.
DR Proteomes; UP000224567; Chromosome 3.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR002365; Terpene_synthase_CS.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF77; CYCLOARTENOL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
DR PROSITE; PS01074; TERPENE_SYNTHASES; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000224567};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 99..401
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 414..721
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 840 AA; 96316 MW; 0FBF13471334F727 CRC64;
MWKLKIAKGE DDPYLCSTNN YVGRQTWEFD PNAGTTEERA EIEEARELFW NNRYKVKPCS
DLLWRMQFLR ETNFEQRIPS VKVDEGEEIS HEVATNALRR AVHFFSALQA TDGHWPAENS
GPLFFLPPLV MCMYITGHLN TIFPAEHRKE ILRYIYCHQN KDGGWGLHVE GQSTMFCTSL
SYICMRILGE GPDGGEKNAC SRARKWILDH GSVVAIPSWG KTWLSILGVF EWLGTNPIPP
EFWIIPSFLP VHPAKMWCYS RMVYMPMSYL YGKRFVGPIT PLILKLREEL YDQPYDEINW
KRVRHLCAKE DLYYPHSLVQ DLMWDSLYIC TEPLLIRWPF NKLRNKALEA TMKHIHYEDE
NSRYITIGCV NKVLCMLACW VEDPNSHYFK KHLARIPDYL WVAEDGMKMQ SFGSQTWDTS
LAIQALLASE MYDEISDTLR KGHNFLKKSQ VKDNPSGDFK RMYRHISKGS WTFSDQDHGW
QASDTTAEAL RCCLLFSTMP SELVGPAMES ARLYDSVDVI LSLQSKKGGV AAWEPAGASE
YLELLNPTES FADNVIEHEY VECTGSSIQA LVRFKKLYPG HQTAEIDNFI DNAVKYVEDV
QKPDGSWYGS WGVCFTYAAW FALGGLAAAG KSYSNCATVR KGVEFLLRTQ RSDGGWGESY
RSCPDKVYRE LETDYSNLVQ TAWALMGLIH SDQADRDPRP LHRAARLLIN SQMEDGDFAQ
QTKDLNRLNY FLGIEVAKSR SDPNTKLLPG QGEPLNDPGI YRRLVVHQME KHGERHAKNE
AIPAVRQDHK KLYWVLSSSL ECANCPSSFP DYMGNGWLKP NGQYTISSGF KWRLGEGPQK
//
