ID A0A2G2XGA8_CAPBA Unreviewed; 666 AA.
AC A0A2G2XGA8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Transmembrane and coiled-coil domain-containing protein 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CQW23_05014 {ECO:0000313|EMBL:PHT56528.1};
OS Capsicum baccatum (Peruvian pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=33114 {ECO:0000313|EMBL:PHT56528.1, ECO:0000313|Proteomes:UP000224567};
RN [1] {ECO:0000313|EMBL:PHT56528.1, ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RC TISSUE=Leaf {ECO:0000313|EMBL:PHT56528.1};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
RN [2] {ECO:0000313|Proteomes:UP000224567}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. PBC81 {ECO:0000313|Proteomes:UP000224567};
RA Kim S., Park J., Yeom S.-I., Kim Y.-M., Seo E., Kim K.-T., Kim M.-S.,
RA Lee J.M., Cheong K., Shin H.-S., Kim S.-B., Han K., Lee J., Park M.,
RA Lee H.-A., Lee H.-Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E.,
RA Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.-C., Kwon J.-K.,
RA Lee H.-Y., Koo N., Hong Y., Kim R.W., Kang W.-H., Huh J.H., Kang B.-C.,
RA Yang T.-J., Lee Y.-H., Bennetzen J.L., Choi D.;
RT "Multiple reference genome sequences of hot pepper reveal the massive
RT evolution of plant disease resistance genes by retroduplication.";
RL J. Anim. Genet. bioRxivorg:115410-115410(2017).
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT56528.1}.
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DR EMBL; MLFT02000002; PHT56528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G2XGA8; -.
DR Proteomes; UP000224567; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR PANTHER; PTHR17920:SF21; TRANSMEMBRANE_COILED-COIL PROTEIN (DUF726); 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000224567};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 305..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 33..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 72362 MW; B5739239F0A21ADB CRC64;
MSSSTLTPMQ RYAAGALFGL ALHQAQIHQT CPLGFPSDED NNERISNSSS NDSVSDDPHL
WVHQSSGLLR PVFKFLEIDE KAWSGLEETA GLSSPKHHVG GFLRSLSVSE EGADASSEAA
EKELDLAKAI DAMASSMERA SHDVSKKEKQ REYEDKCREK LSLADTQSWS EVKNTTNIEN
YQEKSKKSSS IEQAHLESVS GFDKKPVEEA STLEYSRKVT VLYQLFSACL SQSPEESKKY
TRRRGYDARH RVALHLLATW FDIKWIKVEA IETTIACSAM ALKEEELKEQ SRSPKSSWAK
WKRRGIIGAA AVTGGTLLAV TGGLAAPAIA AGFGALVPTL GTLVPVIGAS GFAAVAGAAG
SVAGSVAVAA SFGAAGAGLT GFKMARRTGD VDEFEFKALG ENHNQGRLAV EVLISGLVFK
EEDFVRPWEG QHDNSERYVL QWESKNLIAV STAIQDWLTS RLAMELMKRG AMMTVLKTLL
AALALPATLL AMTDFIDSKW AVAVDRSDKA GKLLAEVLQK GFQGHRPVTL VGFSLGARVI
FKCLQILAES ENNSGLVERV FLLGAPIAIK NMNWEAARKV VAGRFVNAYA TNDWMLGIAF
RASLLARGLA GIQPVDVPGI ENVDVTELID GHSSYLWATQ RILDLLELDA YYPVVLGRVA
LQRQTS
//
