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Database: UniProt
Entry: A0A2G2Y0A0_CAPAN
LinkDB: A0A2G2Y0A0_CAPAN
Original site: A0A2G2Y0A0_CAPAN 
ID   A0A2G2Y0A0_CAPAN        Unreviewed;      1963 AA.
AC   A0A2G2Y0A0;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   05-JUN-2019, entry version 9.
DE   RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442};
DE            EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442};
GN   ORFNames=T459_32983 {ECO:0000313|EMBL:PHT63174.1};
OS   Capsicum annuum (Capsicum pepper).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Solanoideae;
OC   Capsiceae; Capsicum.
OX   NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT63174.1, ECO:0000313|Proteomes:UP000222542};
RN   [1] {ECO:0000313|EMBL:PHT63174.1, ECO:0000313|Proteomes:UP000222542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX   PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA   Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S.,
RA   Lee J.M., Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M.,
RA   Lee H.A., Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E.,
RA   Lee S.E., Jeon J., Kim H., Choi G., Song H., Lee J., Lee S.C.,
RA   Kwon J.K., Lee H.Y., Koo N., Hong Y., Kim R.W., Kang W.H., Huh J.H.,
RA   Kang B.C., Yang T.J., Lee Y.H., Bennetzen J.L., Choi D.;
RT   "New reference genome sequences of hot pepper reveal the massive
RT   evolution of plant disease-resistance genes by retroduplication.";
RL   Genome Biol. 18:R210.1-R210.11(2017).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-
CC         COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000442}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC       {ECO:0000256|RuleBase:RU000442}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PHT63174.1}.
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DR   EMBL; AYRZ02000043; PHT63174.1; -; Genomic_DNA.
DR   Proteomes; UP000222542; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016035; C:zeta DNA polymerase complex; IEA:InterPro.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0019985; P:translesion synthesis; IEA:InterPro.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR030559; PolZ_Rev3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   PANTHER; PTHR45812; PTHR45812; 1.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 2.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|RuleBase:RU000442};
KW   Complete proteome {ECO:0000313|Proteomes:UP000222542};
KW   DNA replication {ECO:0000256|RuleBase:RU000442};
KW   DNA-binding {ECO:0000256|RuleBase:RU000442};
KW   DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442};
KW   Iron {ECO:0000256|RuleBase:RU000442};
KW   Iron-sulfur {ECO:0000256|RuleBase:RU000442};
KW   Metal-binding {ECO:0000256|RuleBase:RU000442};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442};
KW   Nucleus {ECO:0000256|RuleBase:RU000442};
KW   Reference proteome {ECO:0000313|Proteomes:UP000222542};
KW   Transferase {ECO:0000256|RuleBase:RU000442};
KW   Zinc {ECO:0000256|RuleBase:RU000442};
KW   Zinc-finger {ECO:0000256|RuleBase:RU000442}.
FT   DOMAIN       55    196       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN     1104   1302       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN     1369   1816       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     1862   1935       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION      871    891       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2G2Y0A0}.
FT   REGION     1015   1035       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2G2Y0A0}.
FT   REGION     1070   1089       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2G2Y0A0}.
SQ   SEQUENCE   1963 AA;  219038 MW;  C13C76B14F6B112D CRC64;
     MEDSQNDLKF FSVRIVSIDY YMSPPLPAFD ISYSTFQGGR VNEVPVIRVY GATPAGQKTC
     LHLHGALPYF YVPCSELSLQ SDEKGSECTN ALARALEKVL KLKGSAGSKR QHVHGCSLVR
     ARKFYGYHSS EELFLKIYFY HPQDVSRAAN LLLGGAVLDK SLQPHESHIP FLLQFLVDYN
     LYGMGHLHVS KMKFRNPIPD TFSPRKANYI DRRSSDMSTS MTAEFQVDLD GEACFDTRIW
     ISSTIPDDWM WKYSSQADTS TDPDIPNIKR QSISELEGDA IVDAIVNQQL ISYMSVSQTC
     SQEKMVQSLI PIWEEEFARN GVYEVGLPPD PGKPLQDDVL KTLSHGIGYE EILMELSNDV
     KVSSDMLQSI TSSMNDGNIA NVEHGGSLNS IREPSKCSKE GLFQDHVVEK REETDACPKQ
     LLVDQMEATV SVVPSQDVKA SDQDALRLLN WLASSQAAED INSDDDLAQE TILSPSMPAT
     TIDTVLEKAN VAYENESQQE CEDILDSVRD CYFEELERKT SQSISNNRSC RSSSSMIIPQ
     LDGSNDDPNP FPFVNDSSET YKKFGRSSQA DSWNKATLAT NNKHRNKRPG WCSLPIALGQ
     NLNDSHPNPV HTPSSHICDE RAGRRTSSHM NFNEQPNFLT RNLNKSANCE EKSSTIVECS
     TRDLMRVKRS YQAEPSEYGN QVKKVQIGAE GREDSFLYSE SNHDKKEKRL RDSLISRTAI
     TDQPRECNER SSYLALQLQA EPGDIKADKS NCPSYCKLPL SSSSLLTNAS KDGVLLSSEG
     PHVEVVSRAS AGFQRSASTS QGTKDIFQLP DVENQKSTIY MGSCGCCSRE NVDSCMKCLS
     QYPAGPSHSI STVTGVSGDV SELIGMTFSK KPPKAEFTDE PGRSVQSARG APSYHVVKNK
     TRTCVQDRDL DECPPFFEGN DLVGEKICSI KYGTDDYAHC QDSVLGVPVH YQNDGSYLYM
     LTHVYSPPRS ECVRQWLSVD CIDSSKMDVV SGPPMNPSTK VCSDDVAELQ DSQSTFGDQP
     LMDSASASEP NTNQLQAKEN CQESTGVHDA RMKQQDEEII LKYNPSLGGS QNLSQISGPD
     RKSRLTPLSQ TGFRDPASIG CGQQLTILSI EVQAESRGDL KPDPRFDAVR IVVLFFQEDD
     DFRSDTHVLL HCNGQSVQRD LDGVSECKVL TFSEERQVFF HFIKIIKSFD PDIFMGWDIQ
     GGSLGFLAER AAYLGIGLLN KISRSPSEGN IASRDSEGGK LSDIFSDAVA ADPMSHEDAA
     IIDDEWGRTH ASGVHVGGRI VLNIWRLMRG EVKLNLYTLE AVAEAVLRRK IPYIPNKVLT
     NWFLSGPGRA RYRCIEYFLE RAKLNLQIMN QLDVVNRTSE LARIFGIDFF SVLSRGSQYR
     VESMFLRLAH AQNYVAISPG NQQVASQPAM ECIPLVMEPK SGFYADPVVV LDFQSLYPSM
     IIAYNLCFCT CLGKVTSTKA NILGVSSYSP DKNVVHNLKD EILLTPNGVM YVPPRVRKGV
     LPRLLEEILD TRIMVKTAMK KLAPGQQVLH RIFNARQLAL KLIANVTYGY TAAGFSGRMP
     CAELADSIVQ CGRRTLECAI SFVNTNHRWN AKVIYGDTDS MFVLLEGRSV EEAFRIGHEI
     ASEVTAMNPN PVTLKMEKVY DSCFLLTKKR YVGYSYENIV QSKPVFDAKG IETVRRDTCG
     AVSKIMERSL RVFFEYRDIQ KVKSYLVRQW KKIISGRVSL QDFVFAKEVR LGTYSAQTSS
     LPPAAIVATK AMRVDPRAEP RYAERVPYVV VHGEPGARLA DVVVDPLDVL SIDSPYRLND
     IYYIKKQIIP ALQRVFGLVR ADLNQWFSDM PRTEREAAGK RHLVAANAHR TRIDYYYLSK
     HCIICGELIQ ASSYVCQNCS RNEAVVAAAL TGRTSMLERN IQHLAAICRH CGGGDWFVES
     GVKCTSLACS VFYERRKVQK ELQSLSAVTT DTGFYPRCVV EWF
//
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