ID A0A2G2YZZ2_CAPAN Unreviewed; 1212 AA.
AC A0A2G2YZZ2;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=T459_18828 {ECO:0000313|EMBL:PHT75306.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT75306.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT75306.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT75306.1}.
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DR EMBL; AYRZ02000007; PHT75306.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G2YZZ2; -.
DR EnsemblPlants; PHT75306; PHT75306; T459_18828.
DR Gramene; PHT75306; PHT75306; T459_18828.
DR OMA; IAFIMIR; -.
DR Proteomes; UP000222542; Chromosome 7.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0033612; F:receptor serine/threonine kinase binding; IBA:GO_Central.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF585; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 12.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00365; LRR_SD22; 9.
DR SMART; SM00369; LRR_TYP; 14.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000222542};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1212
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013794117"
FT TRANSMEM 874..897
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 932..1205
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 971
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1212 AA; 134055 MW; B744F69D818CBD0D CRC64;
MEKAFTFFLS TLFLLMASSV MSQTNITTDQ LALLSLKSQI ISDPFHLLDE SWSPVRSVCQ
WVGVTCDFRH QRVKSLNLSS MDLSGRIPPD LGNLSFLVSL DLESNNFHGN LPQEMTRLRR
LKFLDLSFNN FSGKVPPWFG FLHQIQVLSL RNNSFTGSLP SSIFNISKLE MLNLAFNSLE
GHIPVSLSNA SRLQTLELSY NSLQGDIPEG IGNLPNMNWL SIQHNQLTGS IPFTVFNISR
IEIIAFTGNS LSGNLPNGLC NGLPILKELY LTGNKLFGHM PTSLSNCSQL QVLSLSKNEF
DGPIHSEIGR LSDLQQLYLG ANHFTVIFYL FTSKKNKLIN YTLTAGIIPQ EIGNLANLME
LSMEVNQITG SVPISIFNIS VLQVLSLWGN DLNGFLPRDI GNLTEMQFLY LQQNRFTEVQ
LVVVNSLVFL FFLVLTGEIP NEISNLVVLE KLNLQSNSFS GSLEMETFNI SGLRVISLAN
NNLSGSLPPN IGSILPNIEE LNLGSLTNLV GTIPHSISNC SELTILELSN NQLTGLIPNS
IGYLTYLQYL NLALNNLTSD SSLSFLTFLT NCRNLTALSL TLNPLNGMLP ASTGNLSTSL
RNFYANVCKI KGRIPNEVGN LSSLLDLDLS RNYLVGSIPT SIGNLRNLQG LFLSNNKLTG
SIGDNLCKLQ SLDVIDLTQN QFSGSLPNCL GKITSLREIR MGSNKLSTNI PPSLGNIQDL
VVLDLSSNNM VGSLPLEIGN LKAATLIDLS MNQFSNRIPR EIAGLQNLAH LSLRHNKLQG
TIPDSMSNMV GLEFLDLSHN NISGIIPKSL EKLKNLKYFN VSFNKLYGEI PSGGPFKNLS
SQFFIYNEAF CGSSRFSVPP CPTSSKNISN RKKLLVLFLL LAIAVVFVPM TFVLLWIRYR
RGKSAPQQAE SLSTVTRERI SYYELLQTTD DLSESNLIGI GSFGSVYKGV LRSGTAIAVK
VFNLQLDAAF KSFDTECEVL RSLRHRNLVK VITSCSNLDF KALVLDYMPN GSLEKYLYSH
NYFLDIKQRL SIMIDVACAL EYLHHGCSLP VIHCDVKPSN VLLDEDMVAH LSDFGISKLL
GEDPGDLYTK TLATLGYIAP EYGLEGLVST KCDIYSYGVM LLETFTRRKP NEFEGDLSLK
QWASYSLPDA VMEIVDANLL TSTGNRLKKE LDVVASIMKV ALDCCNESPT RRTNMKDVVG
MLQKIKIQLL AC
//
