ID A0A2G2Z6U7_CAPAN Unreviewed; 445 AA.
AC A0A2G2Z6U7;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN ORFNames=T459_15779 {ECO:0000313|EMBL:PHT77727.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT77727.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT77727.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT77727.1}.
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DR EMBL; AYRZ02000006; PHT77727.1; -; Genomic_DNA.
DR STRING; 4072.A0A2G2Z6U7; -.
DR EnsemblPlants; PHT77727; PHT77727; T459_15779.
DR Gramene; PHT77727; PHT77727; T459_15779.
DR Proteomes; UP000222542; Chromosome 6.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022667};
KW Reference proteome {ECO:0000313|Proteomes:UP000222542}.
FT DOMAIN 234..297
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 301..438
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 445 AA; 51851 MW; 08434D76EFA3E982 CRC64;
MIELLLIILT DMPKDFIHHD KLFDLLARVG AHTTKVSTLV RDLEEKSRNE ESTDETIRAT
RDLLKNIELF KEDLKNDYLK APDPSQRCFP MNDGPLFMHL LQIHLNDLLD SNAYSIVLIK
EEIGLVKEDL EFIRSFFANI DQEFCKDLWA RILDVEYEEK DVIDSIIVQD NDLIHFIFSL
PYTVRKIKLI REEVSNFPEK IRKNKSLIVV NSPKKPVESK SLTAGKIIVG FEEETNWIIS
KLISKPKDLD VISITGMPGS GKTTLASKVY NDESVCSHFD LRAWCTFDQE YDEKKLLVXC
SHFDLRAWCT FDQEYDEKKL LVTLFNLVTG SDLKFCEDID VADKLRRKLH GKRYLIVLDD
VWDTTTWDEL TRPFPKVEKG SRIILTTREK KVAFHGKCNT DPHNNLRLLR PEESWELLEK
REFGKDCCPD ELLDVGKEKD ENKHN
//
