ID A0A2G2Z858_CAPAN Unreviewed; 806 AA.
AC A0A2G2Z858;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=ATP-dependent zinc metalloprotease FTSH 7, chloroplastic {ECO:0000313|EMBL:PHT78187.1};
GN ORFNames=T459_16239 {ECO:0000313|EMBL:PHT78187.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT78187.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT78187.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT78187.1}.
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DR EMBL; AYRZ02000006; PHT78187.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G2Z858; -.
DR STRING; 4072.A0A2G2Z858; -.
DR EnsemblPlants; PHT78187; PHT78187; T459_16239.
DR Gramene; PHT78187; PHT78187; T459_16239.
DR OMA; NSSCEHD; -.
DR OrthoDB; 117at2759; -.
DR Proteomes; UP000222542; Chromosome 6.
DR GO; GO:0009534; C:chloroplast thylakoid; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IBA:GO_Central.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF49; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 9, CHLOROPLASTIC; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000313|EMBL:PHT78187.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000222542};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT DOMAIN 361..501
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 68..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 87983 MW; 4755D432F817EAD0 CRC64;
MATTIRPFIH VQISLNFHYN NHPKCLYNKH TTFSFFSNRY GFLHEKKSIS RKSLHGFQFF
GQKKSKKKIR VNGSCEQDSD SSEKPESSAT DSKNSPGQEP GRVPNSGSSS RREKQGKDNW
WGKKLRWEPI VQAQEIGVLL LQLGIVMFVM RLLRPGLPLP GSDPRAQTMF VSVPYSEFLS
KINSNQVQKV EVDGVHIMFK LKNDVMSSST SVVVENEVVS KLQDSEAALL RSVNPTKKIV
YTTTRPSDIK TPYEKMVEND VEFGSPDKRS GGFMNSALIA LFYIAVLAGL LHRFPVNFSQ
STAGQLRNRK SGSSGGTKVS ELGETITFAD VAGVDEAKEE LEEIVEFLRN PDKYIRLGAR
PPRGVLLVGL PGTGKTLLAK AVAGEAEVPF ISCSASEFVE LYVGMGASRV RDLFSRAKKE
APSIIFIDEI DAVAKSRDGK FRIVSNDERE QTLNQLLTEM DGFDSNSAVI VLGATNRADV
LDPALRRPGR FDRVVMVETP DRIGREAILK VHVSKKELPL AQDVDLGNIA SMTTGFTGAD
LANLVNEAAL LAGRLNKVLV ERVDFIQAVE RSIAGIEKKT AKLQGSEKAV VARHEAGHAV
VGTAVANLLS GQPRVEKLSI LPRSGGALGF TYIPPTNEDR YLLFVDELRG RLVTLLGGRA
AEEVLYSGRV STGALDDIRR ATDMAYKAVA EYGLSQTIGP ISVATLSGGG MDDGGSMPWG
RDQGHLVDLV QREVRALLQS ALDIALCVVR ANPKVLEGLG AQLEENEKVE GEELQEWLSM
VIAPAELTFF VKGKQGSLLP LQAGSG
//
