ID A0A2G3A6D6_CAPAN Unreviewed; 1009 AA.
AC A0A2G3A6D6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=T459_04907 {ECO:0000313|EMBL:PHT89794.1};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000313|EMBL:PHT89794.1, ECO:0000313|Proteomes:UP000222542};
RN [1] {ECO:0000313|EMBL:PHT89794.1, ECO:0000313|Proteomes:UP000222542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. CM334 {ECO:0000313|Proteomes:UP000222542};
RX PubMed=29089032; DOI=10.1186/s13059-017-1341-9;
RA Kim S., Park J., Yeom S.I., Kim Y.M., Seo E., Kim K.T., Kim M.S., Lee J.M.,
RA Cheong K., Shin H.S., Kim S.B., Han K., Lee J., Park M., Lee H.A.,
RA Lee H.Y., Lee Y., Oh S., Lee J.H., Choi E., Choi E., Lee S.E., Jeon J.,
RA Kim H., Choi G., Song H., Lee J., Lee S.C., Kwon J.K., Lee H.Y., Koo N.,
RA Hong Y., Kim R.W., Kang W.H., Huh J.H., Kang B.C., Yang T.J., Lee Y.H.,
RA Bennetzen J.L., Choi D.;
RT "New reference genome sequences of hot pepper reveal the massive evolution
RT of plant disease-resistance genes by retroduplication.";
RL Genome Biol. 18:R210.1-R210.11(2017).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHT89794.1}.
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DR EMBL; AYRZ02000002; PHT89794.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G3A6D6; -.
DR EnsemblPlants; PHT89794; PHT89794; T459_04907.
DR Gramene; PHT89794; PHT89794; T459_04907.
DR OMA; NMMELEV; -.
DR Proteomes; UP000222542; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProt.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF451; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 6.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 7.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000222542};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1009
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013653128"
FT DOMAIN 724..1000
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 751
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1009 AA; 110684 MW; C0E2878A2F6A5C29 CRC64;
MEKGCIHLAV VLLLLQQMSS CLSIANITTD QTALLALQSQ ISLYDPRNVL ARNWTIFTPV
CSWIGVTCGL RHQRVTALNI VSMNLKGMIP PQLGNLSFLN SLNIRNNSFH GSLPMELARL
RRLKMINAMS NNFTGAIPSF LGLLPNLQSL YLAFNQLSGN IPPSLFNITK LKYLRLRGNI
LGGEIPRVIN SLCCLNFIDL QDNKLTGAIP PTMFNQSSLK QIGLTNNILY GKLPGNICDN
LPNLEVLALS KNRFDGLIPP NLQNCSKLQI LSLSANDFTG TIPAEIGNLT MLTSLQLGLT
YLKVTCVLFP NLSGEIPREL GNLQRLQIFG LYQNRLSGSI PASLFNISTL QILTVVDCQL
SGSLPSNLGQ GTPNLEEIYL GINNLSGVFP ASISNASRLT DLDLSNNMFS GSIPDSLGNL
ELLELLQLGQ NLLINQNFST ELTFLTSLTR CRNLRELVIR DNPLNGILPA SIGNFSSSLK
IFSASRCKLS SIVPEEIGNL TDVLGISLFG NDLTGFIPKT IGGLQKLQIF LIESNMLSGT
IPDEICCLQN IVDLSIRKNK ISGPLPSCLG NVTTLRNLYL ASNKLNSSLP ERLWSLQDLL
VLDAASNSFS GVLSPQIGNL KAVIDIDLSY NDFSGMIPST MGDLQKLVSL SLSHNRIDGP
IPESFGKMLS LELLDLGYNN LTGEIPKSLE SLLYLKYLDV SFNKLMGEIP TGGPFGNFTA
TNGFSGDNLL GTGSFSKVYK GVNNGTLFAV KVFKLEPEGA FKSFDTECEI LRNLRHRNLT
KVITSCSTPI FKALILEYMP NGTLEKWLHS HDFFLDMLPR LDIFIDVASA LDYLHNGYSE
PVVHCDLKPS NILLDQNMVS HLSDFGIAKF LGGENCFRQT KTIGTIGYIA PEYGQDGLVS
TSCDVYSFGI VMMEAFTRRR PSDEMFTGDL SLKHWINDSL PNGAAQMLDA DLIRQKEESL
NAKIQCFVSV MELALSCTSL SRDARINMKE ALLGLKNIRL QLITSSTLE
//
