ID A0A2G3E1C0_9FIRM Unreviewed; 1186 AA.
AC A0A2G3E1C0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894,
GN ECO:0000313|EMBL:PHU37021.1};
GN ORFNames=CSX02_10020 {ECO:0000313|EMBL:PHU37021.1};
OS Agathobacter ruminis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Agathobacter.
OX NCBI_TaxID=1712665 {ECO:0000313|EMBL:PHU37021.1, ECO:0000313|Proteomes:UP000224563};
RN [1] {ECO:0000313|EMBL:PHU37021.1, ECO:0000313|Proteomes:UP000224563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JK623 {ECO:0000313|EMBL:PHU37021.1,
RC ECO:0000313|Proteomes:UP000224563};
RA Sheridan P.O., Walker A.W., Duncan S.H., Scott K.P., Toole P.W.O., Luis P.,
RA Flint H.J.;
RT "Resolving the taxonomy of Roseburia spp., Eubacterium rectale and
RT Agathobacter spp. through phylogenomic analysis.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHU37021.1, ECO:0000313|Proteomes:UP000224563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JK623 {ECO:0000313|EMBL:PHU37021.1,
RC ECO:0000313|Proteomes:UP000224563};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHU37021.1}.
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DR EMBL; PDYG01000087; PHU37021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G3E1C0; -.
DR Proteomes; UP000224563; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000224563}.
FT DOMAIN 521..638
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 167..201
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 255..380
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 414..471
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 672..874
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 988..1015
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1186 AA; 135727 MW; C194FAD971FBB57E CRC64;
MYLKCLEVHG FKSFANKIVF DFHNGITGIV GPNGSGKSNV ADAVRWVLGE QSAKQLRGAS
MQDVIFAGTE NRNPQSYAYV AITLDNSDHQ LALDYEEVTI ARRVYRSGES EYLINGNVCR
MKDVKELFYD TGIGKEGYSI IGQGQIDRIL SNKPEERREL FDEAAGIVKF KQRKNETQKQ
LENERENLVR VNDILAELER QVGPLERQSE KAKTYLKKRE ELKTYDINMF LLESARIRGM
QEQTDSNFAI ADKELAEVKE QHETIKGEYE NLKEEIALLE SNITRVQEEI NQSSVTKQRL
ENQIELLQEQ IHTAEMTDEH LSGRLQAIDA DKAEREKEKS EYESKRAAFD EKNALIAERK
QTAQEELAAI QQEIARCNTG IENGQAEMIR LLNNKASIKA RQQKMDTMLE QTNIQKAQLN
QRLLSRKSRE AEQETYFAQT EQEFQEIAKR LEEKKAEEKK LSEKDKEWKT KAQENAQEIQ
TVRLEQNKIE TRLESLRNIA ERYEGYGNST RRVMEQKDSN PGVLGVVSDL ISTDKKYETA
IETALGGNIQ NIVTEDEQCA KKMIAFLKEN RLGRATFLPL TSVRASHNDK NKDSLKEPGV
LGIASELVKC DDKYREVAAY LLGRVLVVDT VEHALALAKK NHYSQHMVTL EGEYLSPGGS
LTGGAFKNNS NLLGRKRELD DMKKRLADLQ KEGEKLLARK DEIEMARALG EEELNEVRIA
LQKLLLEENT AKLNFEQAKK RKEESDQAYE SLRNETAELD GNIREITAEK QKIEDEEAYA
KRRESEIAEE KEEFARIIKE QSALEEAATS KLSEISLEEA NIVQRVGFVN ENIERLNREI
AKLDTEREDL IEGAKTAKSD VEQKRKNIEE IQQTIASGND IFAQLSDSLR KARADKEEKT
EIYSGFFQKQ EDISKRETDL EKEIVRLSTQ QEKLKEALDY QTNYIWETYE LSPHAAEELR
NEEYDDLAAL KKLISRIRDE IRSLGDVNVN AIEEYKEVSE RYEFLKNQHD DLIIAEERLV
DIIEELDEGM RKQFTEKFAD IQKEFDKTFK HLFGGGHGTL ELQEDEDILE AGIRVIAQPP
GKKLQNMMQL SGGEKALTAI ALLFAIQALK PSPFCLLDEI EAALDDSNVV RYAGYLKKLT
KDTQFIVITH RRGTMNAADR LYGITMQEKG VSTLVSVNLI ENDLEE
//
