ID   A0A2G3E1Q8_9FIRM        Unreviewed;       628 AA.
AC   A0A2G3E1Q8;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   RecName: Full=HD-GYP domain-containing protein {ECO:0000259|PROSITE:PS51832};
GN   ORFNames=CSX02_09250 {ECO:0000313|EMBL:PHU37184.1};
OS   Agathobacter ruminis.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Agathobacter.
OX   NCBI_TaxID=1712665 {ECO:0000313|EMBL:PHU37184.1, ECO:0000313|Proteomes:UP000224563};
RN   [1] {ECO:0000313|EMBL:PHU37184.1, ECO:0000313|Proteomes:UP000224563}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JK623 {ECO:0000313|EMBL:PHU37184.1,
RC   ECO:0000313|Proteomes:UP000224563};
RA   Sheridan P.O., Walker A.W., Duncan S.H., Scott K.P., Toole P.W.O., Luis P.,
RA   Flint H.J.;
RT   "Resolving the taxonomy of Roseburia spp., Eubacterium rectale and
RT   Agathobacter spp. through phylogenomic analysis.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PHU37184.1, ECO:0000313|Proteomes:UP000224563}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JK623 {ECO:0000313|EMBL:PHU37184.1,
RC   ECO:0000313|Proteomes:UP000224563};
RA   Banno H., Chua N.-H.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHU37184.1}.
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DR   EMBL; PDYG01000074; PHU37184.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G3E1Q8; -.
DR   Proteomes; UP000224563; Unassembled WGS sequence.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   Pfam; PF01966; HD; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000224563}.
FT   DOMAIN          397..610
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
SQ   SEQUENCE   628 AA;  74035 MW;  72810E026CAAE4AB CRC64;
     MTIMNDEQTN KINIEKDFEQ YVERMKRIRA LATPDITEIK TADEYSKVLI DHFRQIGVLA
     EQNYALIEDY IMPMRLPREE LERFNEMLVN EIDAVEVDVH LSDWLMDKLM LSDIEMHSGQ
     DDSSLLSRLF VQMRRAYYRI ASFSRYHDYE SERVREQIIK DAKIVDDYLA KERFAQLSVE
     ARRILIECVK FAPQLYNNNE YPLSDEYCNE QFAIVERALS VCRDSFYRKL MPDYDWQSYK
     MYVHLYACYM IYADISQETA HKVYRYIKKL KGIVRRSHSR FKLGDWLDYK TRDFEMWALV
     VSGKENILEA GKRCYRSYSR RNQYDYSDTG ILKNLDLPAS FISLVKNHPV PFDEDLAKKY
     EAMAKGMLEY LYRIPKLSSQ YFRCMIIFIN LLMNYMEMPG ILSMEDLCLN AFITLHPPSY
     IHSRMVAQIS SCLSRHLAQL HPELLEERWK DNRFGFQMYA YHAGLCHDIG KLFIIDTICM
     YGRPLFDEEF EIIKKHPSVG AGVARKYDSL RDYMDVIRYH HVWYDGSRGY PDCPQGLGGV
     RNTAINIVHM ADCMDAATDV VGRSYKAAKT LDQFIAEAKA GSGTEFAPYV VELLQNEKVK
     QELDFLLYQG RQNLYQETYL MLMQMKGK
//