ID A0A2G3E5Y7_9FIRM Unreviewed; 595 AA.
AC A0A2G3E5Y7;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=CSX02_01580 {ECO:0000313|EMBL:PHU38664.1};
OS Agathobacter ruminis.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Agathobacter.
OX NCBI_TaxID=1712665 {ECO:0000313|EMBL:PHU38664.1, ECO:0000313|Proteomes:UP000224563};
RN [1] {ECO:0000313|EMBL:PHU38664.1, ECO:0000313|Proteomes:UP000224563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JK623 {ECO:0000313|EMBL:PHU38664.1,
RC ECO:0000313|Proteomes:UP000224563};
RA Sheridan P.O., Walker A.W., Duncan S.H., Scott K.P., Toole P.W.O., Luis P.,
RA Flint H.J.;
RT "Resolving the taxonomy of Roseburia spp., Eubacterium rectale and
RT Agathobacter spp. through phylogenomic analysis.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHU38664.1, ECO:0000313|Proteomes:UP000224563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JK623 {ECO:0000313|EMBL:PHU38664.1,
RC ECO:0000313|Proteomes:UP000224563};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHU38664.1}.
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DR EMBL; PDYG01000004; PHU38664.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G3E5Y7; -.
DR Proteomes; UP000224563; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR CDD; cd00315; Cyt_C5_DNA_methylase; 1.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018117; C5_DNA_meth_AS.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR031303; C5_meth_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR46098; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR46098:SF1; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00094; C5_MTASE_1; 1.
DR PROSITE; PS00095; C5_MTASE_2; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000224563};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 292
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 595 AA; 68852 MW; 55C6A875DEB4E678 CRC64;
MIRLATCFSG IGAIEHALNR MGLDNKIVFA CDNGDVDILS KSVPVDIEEI KKEFTLLEKI
IRGIESSEDA EELKSDLDHD AELFENQCQK IELVDATIVD LDIFILQQVI EMKEIKKARL
KEYTKFLDSL KKQKGNNLLL HGLMYAIEIL NDYHKDNSWS LLEKTDAKFN SGDKIDWSLI
CSDLVKLKKI IDKLNGRKIL KNTRDISERL GMLHEKIQVL QINNDLNKLS SYDDKKAYID
SLYASKESSN NVKKSYMANY DLDDRHFYWN VSFLDGKEYT NEVDLFVGGS PCQSFSLVGK
QRGLEDTRGT LFYEYARLVK EIKPKVFIYE NVKAILSNDD GRTWETICQV FTDLDYTWSY
QVLNARDYGI PQNRERVFVV GFRNDLNLKK KFEFPKPIEL KTTMKDFLLD NVSGKYYLPS
KGVDFVTSDK NLTKRYTQID GDVALCQKKN QQFNWHGDFV FEEENKDKEK TMQDLEKYFL
SEKVRKYVLA SGTKGFYSRP ETDLDIARPL LTTMHKMHRA GVDNYVTTDG RLRKLTPREC
LRLMGFSDSF KIVVSDTSMY QQSGNSIVVD VLMNIMNQVI ESYPQLLEEE ENGGK
//
