ID A0A2G3JG59_9NEIS Unreviewed; 483 AA.
AC A0A2G3JG59;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Exopolyphosphatase {ECO:0000256|ARBA:ARBA00020416};
DE EC=3.6.1.11 {ECO:0000256|ARBA:ARBA00012451};
GN Name=ppx {ECO:0000313|EMBL:PHV03002.1};
GN ORFNames=CSQ88_04030 {ECO:0000313|EMBL:PHV03002.1};
OS Iodobacter sp. BJB302.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC Chitinibacteraceae; Iodobacter.
OX NCBI_TaxID=1506510 {ECO:0000313|EMBL:PHV03002.1, ECO:0000313|Proteomes:UP000224670};
RN [1] {ECO:0000313|EMBL:PHV03002.1, ECO:0000313|Proteomes:UP000224670}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BJB302 {ECO:0000313|EMBL:PHV03002.1,
RC ECO:0000313|Proteomes:UP000224670};
RA Jude B.A., Perron G.P., O'Brien K., Doing G., Bettina A.M.;
RT "Draft genomes of phenotypically distinct violacein producing isolates
RT cultured from the Hudson Valley Watershed.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate;
CC Xref=Rhea:RHEA:21528, Rhea:RHEA-COMP:9859, Rhea:RHEA-COMP:14279,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16838,
CC ChEBI:CHEBI:43474; EC=3.6.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00000209};
CC -!- SIMILARITY: Belongs to the GppA/Ppx family.
CC {ECO:0000256|ARBA:ARBA00007125}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHV03002.1}.
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DR EMBL; PDZG01000008; PHV03002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G3JG59; -.
DR OrthoDB; 9793035at2; -.
DR Proteomes; UP000224670; Unassembled WGS sequence.
DR GO; GO:0004309; F:exopolyphosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR022371; Exopolyphosphatase.
DR InterPro; IPR048950; Ppx_GppA_C.
DR InterPro; IPR003695; Ppx_GppA_N.
DR InterPro; IPR030673; PyroPPase_GppA_Ppx.
DR NCBIfam; TIGR03706; exo_poly_only; 1.
DR PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR Pfam; PF02541; Ppx-GppA; 1.
DR Pfam; PF21447; Ppx-GppA_III; 1.
DR PIRSF; PIRSF001267; Pyrophosphatase_GppA_Ppx; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 16..297
FT /note="Ppx/GppA phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02541"
FT DOMAIN 304..469
FT /note="Ppx/GppA phosphatase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21447"
SQ SEQUENCE 483 AA; 52987 MW; 9504A0C401D5B947 CRC64;
MIAAVDLGSN SFRLQIARVV EGALFPLDSL KETVRLGAGL DASGSLTPEA QQQAIEALSR
FGERLRGLPV ECVRAVATNT FRVAKNASVF LPQAEAALGF PIEVIAGREE ARLIYIGAAH
SLPATRDKRL VVDIGGGSTE LITGSHFRIF RTESVPMGCV SWSLRFFPDG VITSERLAEA
ELAARGMLLS LVPDFNHEQW QRAVGTSGTA RSIADILELN DFSALGITRE GMDKLRQHIL
AAGHVDKVQL NGLRADRRPV LLGGFAIMMA VFDMLAVERM GVTFGALRDG VLYDLVGRQS
EHDIRHRSVE QFQRRYHVDP YQAERVAILA GKLFTRMVAD DAIGAHRLNM AAALHEVGRS
IAHASYHKHS AYILLHADMP GFSKREQALL ARLVLAHRGG LGKLGDDMID LVEWSAILAL
RLATIFCRSR TDIDLPLLRC EANSKQFLLE LDSAWLEANP LTAYALTEEV NAWQNIGMKL
VVS
//
