ID   A0A2G4EZV0_9CYAN        Unreviewed;       545 AA.
AC   A0A2G4EZV0;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Serine hydrolase {ECO:0000313|EMBL:PHX55029.1};
GN   ORFNames=CP500_013010 {ECO:0000313|EMBL:PHX55029.1};
OS   Tychonema bourrellyi FEM_GT703.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Oscillatoriales; Microcoleaceae; Tychonema.
OX   NCBI_TaxID=2040638 {ECO:0000313|EMBL:PHX55029.1, ECO:0000313|Proteomes:UP000226442};
RN   [1] {ECO:0000313|EMBL:PHX55029.1, ECO:0000313|Proteomes:UP000226442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FEM_GT703 {ECO:0000313|EMBL:PHX55029.1,
RC   ECO:0000313|Proteomes:UP000226442};
RA   Banno H., Chua N.-H.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PHX55029.1, ECO:0000313|Proteomes:UP000226442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FEM_GT703 {ECO:0000313|EMBL:PHX55029.1,
RC   ECO:0000313|Proteomes:UP000226442};
RA   Tett A., Armanini F., Asnicar F., Boscaini A., Pasolli E., Zolfo M.,
RA   Donati C., Salmaso N., Segata N.;
RT   "Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi
RT   isolated from alpine lentic freshwater.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHX55029.1}.
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DR   EMBL; NXIB02000068; PHX55029.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G4EZV0; -.
DR   OrthoDB; 9775096at2; -.
DR   Proteomes; UP000226442; Unassembled WGS sequence.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF4; SLR0121 PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:PHX55029.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000226442}.
FT   DOMAIN          295..505
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
FT   REGION          16..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..112
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   545 AA;  58183 MW;  86678E047E45A77E CRC64;
     MAERFPKRSI LSVLSSISST ESGSEPPQSG KANQSSKSAR RGSPKSQKPQ PEVSTKATVP
     STLPLQPLST SRSRANSSAS TNPPALNPPD FISNPQSAIT GKKLGKSQTP QSKGRQSRKK
     DLAAIDLFDP GAYVENVSAI ASNPNTQLIP PTTPTPRESP LQSPPSRIED TETPPQVKKR
     PAPKPRPQAS KKPRKRPASP STPPLVYATR LLILGVGMAV ICGTMLSVVN AVSRSGVSAQ
     EQKTAIADGQ KTQAESDSAN ATVANPPALQ LNQELAALKT QVQALATENP TLTAGIFLVD
     LDSGSYLNFN GDTTFASAST IKVPILVAFF QAVDDGKVRL DQTLTLRAED IVGGSGEMQD
     QAPGKKYSAL EIARKMIVVS DNTATNMMID LLGGAEVLNQ HFATWGLRAT VLNNKLPDLE
     GTNTTSPKDL INIIAQIDRG NLVSVKSRDR IFQIMQQTKN DSLLPKGLGA EAIIAHKTGN
     INTLLADAGM VDLPNGKRYL VAVMVKHPPE TEKPAQSLIR DISRMSYRYL NDGEATVDSK
     VKIKN
//