ID A0A2G4F6G5_9CYAN Unreviewed; 811 AA.
AC A0A2G4F6G5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=CP500_000115 {ECO:0000313|EMBL:PHX57384.1};
OS Tychonema bourrellyi FEM_GT703.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Tychonema.
OX NCBI_TaxID=2040638 {ECO:0000313|EMBL:PHX57384.1, ECO:0000313|Proteomes:UP000226442};
RN [1] {ECO:0000313|EMBL:PHX57384.1, ECO:0000313|Proteomes:UP000226442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FEM_GT703 {ECO:0000313|EMBL:PHX57384.1,
RC ECO:0000313|Proteomes:UP000226442};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHX57384.1, ECO:0000313|Proteomes:UP000226442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FEM_GT703 {ECO:0000313|EMBL:PHX57384.1,
RC ECO:0000313|Proteomes:UP000226442};
RA Tett A., Armanini F., Asnicar F., Boscaini A., Pasolli E., Zolfo M.,
RA Donati C., Salmaso N., Segata N.;
RT "Draft genome sequence of the planktic cyanobacteria Tychonema bourrellyi
RT isolated from alpine lentic freshwater.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHX57384.1}.
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DR EMBL; NXIB02000001; PHX57384.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G4F6G5; -.
DR OrthoDB; 9765670at2; -.
DR Proteomes; UP000226442; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000226442}.
FT DOMAIN 34..359
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 380..686
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 55..62
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 811 AA; 91440 MW; 40B2C2C1009C4D7B CRC64;
MTDEFDPNFS THSTSSQSEL GAVLREQACQ KIRDSLREAQ KDMANWQGGP LAVSAVPGAG
KSTGMAAAAA IAIARNRLHS RRQLVVVTFT RSAAANIKIK IRERLKELSL PQGGFVVNTL
HGLALNIARR HPSLSGLNLE NSTLVNTTQS HRLIRACVEL WIAENPRRYQ TLLEGQQFDG
EETERMRRQS VLRTEILPQL ANTVIHEAKS SGLFPEDLLE MGAMSFGDSY EILAVAGGLY
QKYQALLRSR EFIDYDEMIL AALRVLADPR ARAIEQKQVF AVFEDEAQDS TPLQTELLAT
LAEDPDHPEL LPNFIRVGDP NQAINSTFTP ADPIYFNNFC DECKEQSKLA EMDVAGRSSQ
IIIDAANFIL EWVNRSELAG TEPPFRHQII EPVPRDDQQI NANPAPIGRG LELYTPRDIY
HTIELIGKRV VQLVEEFLPA GFEWGKSEKY LEFDGEVSDE ENQAKLPLEY LKSMAVLVRE
NKQGKLIKQV LENPQKYGLT VDLSKYGIKI EDVGERDRHS QVPWEILTLL QFLDRPHSPD
YLKAALKILS DRQLIPKQDY NAFTTSPEQF LYPGPLDPKQ SDPVKKCRYF CCSLLQARLE
LPPYQIISFL ALALQYDQTE LATADKLAER VAIQTIGNNS MSNILGVLSE IVTSERFEPV
EAEEKIEERY TSKGQLTIIT MHKAKGLDWD CVFLPFLHDQ IIPGSLRVLP QAKFLGDFTL
AEVARAQIRA SLHKKDAFSN LGEAWEQAGY LKTAEEFRLL YVAMTRAKSL LWMSAEKKGP
FTWNKPDNLQ ELKPCPVMPV LKQKFPDHVI S
//
