ID A0A2G4SH95_RHIZD Unreviewed; 735 AA.
AC A0A2G4SH95;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN ORFNames=RHIMIDRAFT_241873 {ECO:0000313|EMBL:PHZ08134.1};
OS Rhizopus microsporus ATCC 52813.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=1340429 {ECO:0000313|EMBL:PHZ08134.1, ECO:0000313|Proteomes:UP000242254};
RN [1] {ECO:0000313|EMBL:PHZ08134.1, ECO:0000313|Proteomes:UP000242254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 52813 {ECO:0000313|EMBL:PHZ08134.1,
RC ECO:0000313|Proteomes:UP000242254};
RX PubMed=27956601; DOI=10.1073/pnas.1615148113;
RA Lastovetsky O.A., Gaspar M.L., Mondo S.J., LaButti K.M., Sandor L.,
RA Grigoriev I.V., Henry S.A., Pawlowska T.E.;
RT "Lipid metabolic changes in an early divergent fungus govern the
RT establishment of a mutualistic symbiosis with endobacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:15102-15107(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ303867; PHZ08134.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G4SH95; -.
DR STRING; 1340429.A0A2G4SH95; -.
DR OrthoDB; 1348848at2759; -.
DR Proteomes; UP000242254; Unassembled WGS sequence.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF02065; Melibiase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:PHZ08134.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242254}.
SQ SEQUENCE 735 AA; 83912 MW; 9A549094F3FDFC16 CRC64;
MNLSPTSFQN SKAQLCFYYK LDKKLVKHKN ELIQPGGTFS TDAAHVTLKI PPHTNNKGGY
ILSFSVKAKK PIELAQFKAT FMTDLQDQRM LANGFQSWSQ AREMTKNDKI NPIRSSIAWY
TQLNLQGDYD IFQHSGERGV IHSSSYTHFR DMKNVLSFFG SVSEQYGYTY FIGDFNSNSL
SIYKDVSGMR LDKDEEIELV RIFMAQGLDA EAAIWDDYAE FYPDRRCIRG NNMKRHVNGW
TSWYNYYGDV SELVINENVE ALKQFQYPID IFQIDDGFQT AIGDWLSINE KFPSGMKAVA
SKIKNAGFKA GLWLAPYAVG FNSRLAQEHP DWLIINPETK KPVVAGPNWG GFYALDMYHP
GARLYLKEVF DTVLHDWGFD MLKLDFCFAA AMIPRCGKSR GQIMWEAMDL IRDLVGPDKL
VLGCGVPLAC AFRKVDYCRI GSDVAPWWED SKLKLLHVRE RVSTANSLVS TLSRWSMSDR
MFGNDPDVMI IRNQNNKLTP SERYTLCVLN NILGALVFSS DNVALYGQDE HLLYAATFPK
VIAQVKRVLE FRKDCFMVQY SVQNGSVVNQ YTTYSNLTEE EQVIYLPESS KDTHLLFATS
SEMHTAYSDY NEPIFYHPSS EVKLKIHETK TFLHIPPESD SLLLLGTTAH IVPGAELETF
KKEGKDDIKI SFRLENSRRH KVYFALGKYL HTSRSFVPPV CKVNGKQAEH TWIPVHGFGE
GRVKSEVLAF SLEQY
//
