ID A0A2G4SK77_RHIZD Unreviewed; 870 AA.
AC A0A2G4SK77;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=P-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:PHZ09177.1};
GN ORFNames=RHIMIDRAFT_207017 {ECO:0000313|EMBL:PHZ09177.1};
OS Rhizopus microsporus ATCC 52813.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=1340429 {ECO:0000313|EMBL:PHZ09177.1, ECO:0000313|Proteomes:UP000242254};
RN [1] {ECO:0000313|EMBL:PHZ09177.1, ECO:0000313|Proteomes:UP000242254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 52813 {ECO:0000313|EMBL:PHZ09177.1,
RC ECO:0000313|Proteomes:UP000242254};
RX PubMed=27956601; DOI=10.1073/pnas.1615148113;
RA Lastovetsky O.A., Gaspar M.L., Mondo S.J., LaButti K.M., Sandor L.,
RA Grigoriev I.V., Henry S.A., Pawlowska T.E.;
RT "Lipid metabolic changes in an early divergent fungus govern the
RT establishment of a mutualistic symbiosis with endobacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:15102-15107(2016).
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DR EMBL; KZ303860; PHZ09177.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G4SK77; -.
DR STRING; 1340429.A0A2G4SK77; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000242254; Unassembled WGS sequence.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18042; DEXXQc_SETX; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:PHZ09177.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242254}.
FT DOMAIN 290..567
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 575..769
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT COILED 422..480
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 870 AA; 97290 MW; 4A353C2A4377A343 CRC64;
MDNRSANIKA ESASVKALFD TKPKRTTKLL ETPISNEFLQ RKAKRAREQV RKQKIAPNID
NLFKAILSWD ITVTSETPPG RKDLAYIHVP TTFKSFKEYK TAFEPLLVME TWSQIQRAKE
SLSQSDVMER CLVVSRCHTN DFVDITFAMP MSLVTNNISI DDLVCIANHF GTAFFNDPTS
LTEGTEAMKP WRGRAFLGKV ISINQTKNVG EVGIRCYFTS DRISVLNSVS PKTSWSILRI
MSLTTAMREY AALEGLEHFE LGPEILCPTP NTDEKPSASI IQQYCKNYGL NEPQARAIAS
AIQKQYGFSL IQGPPGTGKT KTILALIVSL LDQRSNSTQQ RPIHGKLLVC APSNAAVDEI
TKRLKDGIMT AHGVRRPNVV RIGVADSVNA SVKDRILDRL VEAEMDAAVG NDTTIAKIGA
RLDSLHNEIR NIQIGLDDVD REITQAGGDM VQMSILRGRR KALAQKLAKA RIALKDAHQD
QKNYGQEMEV SRIRARQKVL ANADVVCATL SGSGHDMLTT MGMSFGTVIV DEAAQSVEIS
SLIPLKFDTQ KCVLVGDPNQ LPPTVMSTMA AKYDYQQSLF MRLEKTIGEE VNLIQYRMHP
EISSFPSKLF YQSRLQDGPQ MDKVSSAVWH TLPEFPPYCF FDVYDGQEKM GRGKSIFNTA
EANAAVTLVD LLLTKLPTVK FASKIGVITP YKQQVGQLKA AFQKRFGSNI VDAIDFNTVD
GFQGQEKEII IFSCVRAGSD RGIGFLADMR RMNVGLTRAK FSLFVLGHAS SLARSEYWGE
LVRDAERRSL IREVKENMNT NNLLILNSVD TPTLIIAWTS PGYLKTFTRK NLPPLLLYSQ
IRLQRDRLGY LNQPYQQTHL EWGKNDHRVQ
//
