ID A0A2G4SP87_RHIZD Unreviewed; 349 AA.
AC A0A2G4SP87;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=DHH phosphoesterase {ECO:0000313|EMBL:PHZ10597.1};
GN ORFNames=RHIMIDRAFT_239421 {ECO:0000313|EMBL:PHZ10597.1};
OS Rhizopus microsporus ATCC 52813.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=1340429 {ECO:0000313|EMBL:PHZ10597.1, ECO:0000313|Proteomes:UP000242254};
RN [1] {ECO:0000313|EMBL:PHZ10597.1, ECO:0000313|Proteomes:UP000242254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 52813 {ECO:0000313|EMBL:PHZ10597.1,
RC ECO:0000313|Proteomes:UP000242254};
RX PubMed=27956601; DOI=10.1073/pnas.1615148113;
RA Lastovetsky O.A., Gaspar M.L., Mondo S.J., LaButti K.M., Sandor L.,
RA Grigoriev I.V., Henry S.A., Pawlowska T.E.;
RT "Lipid metabolic changes in an early divergent fungus govern the
RT establishment of a mutualistic symbiosis with endobacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:15102-15107(2016).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
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DR EMBL; KZ303854; PHZ10597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G4SP87; -.
DR STRING; 1340429.A0A2G4SP87; -.
DR OrthoDB; 1342473at2759; -.
DR Proteomes; UP000242254; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016462; F:pyrophosphatase activity; IEA:InterPro.
DR Gene3D; 3.10.310.20; DHHA2 domain; 1.
DR Gene3D; 3.90.1640.10; inorganic pyrophosphatase (n-terminal core); 1.
DR InterPro; IPR001667; DDH_dom.
DR InterPro; IPR038763; DHH_sf.
DR InterPro; IPR004097; DHHA2.
DR InterPro; IPR038222; DHHA2_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF39; EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN); 1.
DR Pfam; PF01368; DHH; 1.
DR Pfam; PF02833; DHHA2; 1.
DR SMART; SM01131; DHHA2; 1.
DR SUPFAM; SSF64182; DHH phosphoesterases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242254}.
FT DOMAIN 202..343
FT /note="DHHA2"
FT /evidence="ECO:0000259|SMART:SM01131"
SQ SEQUENCE 349 AA; 40447 MW; 4304C94DFDDE9C81 CRC64;
MSIGEFLAQL HSSLDKQPRV IVSGNDSADL DSIISSLLFA YFSNLRDKTK TYVPVVKVPR
VDLELRPELK YVFNQVGLDY QQLVCLEQVP SQGDVVLIDH NRATRPFDDN CKWKVTGVLD
HHVDEGFYLN APLRVIRMVG SCVSLVLDHF GNPQLDETLA KLAAAPLLTD TVNLRWELGR
TTDLDVQVFD RLKTHVETTG YFKEIERIKS EVSEMPTEHI LRRDYKEFEV GPYRIGTSSV
NWYFEAWTER DHGYQSITET SLKFAKERKL DLQVIFTAFD HGQNGGYQRQ LAVFVINEKL
RPLQESLEAS KDIGLKPLFD NYYQQENIKM SRKQIWPWIR QWIETNESK
//
