ID A0A2G4T7D8_RHIZD Unreviewed; 1382 AA.
AC A0A2G4T7D8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=RHIMIDRAFT_252455 {ECO:0000313|EMBL:PHZ16919.1};
OS Rhizopus microsporus ATCC 52813.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX NCBI_TaxID=1340429 {ECO:0000313|EMBL:PHZ16919.1, ECO:0000313|Proteomes:UP000242254};
RN [1] {ECO:0000313|EMBL:PHZ16919.1, ECO:0000313|Proteomes:UP000242254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 52813 {ECO:0000313|EMBL:PHZ16919.1,
RC ECO:0000313|Proteomes:UP000242254};
RX PubMed=27956601; DOI=10.1073/pnas.1615148113;
RA Lastovetsky O.A., Gaspar M.L., Mondo S.J., LaButti K.M., Sandor L.,
RA Grigoriev I.V., Henry S.A., Pawlowska T.E.;
RT "Lipid metabolic changes in an early divergent fungus govern the
RT establishment of a mutualistic symbiosis with endobacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:15102-15107(2016).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; KZ303842; PHZ16919.1; -; Genomic_DNA.
DR STRING; 1340429.A0A2G4T7D8; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000242254; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000242254}.
FT DOMAIN 77..229
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1027..1193
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 473..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..940
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..534
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 917..937
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1293..1318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1319..1353
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1354..1368
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1382 AA; 160142 MW; E177A978D6FFEA77 CRC64;
MRDDFLLSDE VLKLQEQEDY YIPNEIDLRG KSDQDLARYL NEITDSIEVS SENISDPVVF
DKILSFLKYF AHLQPRWLAR LFDIILSAFR IEIKTTSDDL ENNQKETFSN HRHCLELYGF
LLHWFLIAVE KNTTTAKITK KKSNQNELKT FDWSNQKLKA FDTASWLLDL KLSKIWTMAP
ERIAFINLFT KPAYQLFENP VNAKSNRVKE RVFRILGLCV KYYDHAFVAQ TTIMQNLQYW
EHSAEPMAEF LVHLVEKQNY HQLADEILRD ISNREFKDTA SKEVKDSPNP KTFSTFLIKL
VELSPKTILK NMALLIHQLD SESYLMRSTM IDILGFMIEE LSKSIEDNAN QMEQINGFFD
ILEEHMLDTI SYCRQRVLQV YLRLFDLKAK FPKRRQAITV LAMRHLQDKS STVRKYVIRV
LCKLILTHPY SMYGGELNID DWKKRLETLN HEINNSTTEE DMPPFIITQA VNNDKDDATS
QKENEEEDDN RSQHSESIND DNRSQHSEGI NDDDVQMDME SQQDKNKEEE HRLTEDKVAK
TVIPAEKLQQ LILMKTYHED AIAFIEQIHT CIPIVTQLLS SKSKAEVLES MDFLVIAYNY
QVKKAQEGIR KMLHLIWTKD TSDEGKGIKM KLLSCYQTLY LEMDRSCSKR ENVNRIAKNL
IQLTYNTNLA ELTSLEQLLK TIMHEDSNKV SDEVIEKLWS VYGFTKGRIQ KMQRRGAIII
LSMLAQANTR IVSEKVDLML KIGFGPLGKS DLSLARYTCI ALQQLQGVKQ MEKSRGVQVG
VRFPLQHSIF TRLKDVLESP TESNEWFSLA EQAINTIYML CEHPETLCQQ LIYQKTVKVF
GDRELTPSFS DTATNAESMI LDYDMSQVQQ NLPFPQNPVH QSSMELSQLF FMVGHVALKQ
IVHLEIIESA WKKKRSQKLE KDGKEKDTHK DAVEEELEQV GGTAEDDIGE AVVRIREKEI
LYGSQSLLAR YGPLLVEVCA RNKLYTNRTL QITATLALAK FMCVSSEFCE KHLQLLFTIL
EKSKDATIRS NVVIALGDMA VCFSTLIDDN ITFLYNRLSD PDTLVKKNAV MVLTHLILNG
MVKVKGQISE MAKCLEDADQ RIADLAKLFF TELASKDNAI YNNLPDIISN LTDKNNPQRL
EEEGFKRVMK FLFSFDFVEK EKQAENIVDK LCQRFLTAGD DERAWRDIAY CLSLLPYKSE
RSLKRLIEGW STYQDKLHED QVHKYFLEII SKCRLQKSQK PEVKSLVDEL EQKIEKVRGP
KESENVDGLQ EDVSAGTTAK RGNTTKTKKR EVKKKTPASE KSPATGVKRR RSRKIEYDEE
SDEEIEEYVA EEDDDEDDED DEEEEEEGNE KDDNDNDNVE KIKNDIEEEE NIEDMDLDEE
ED
//
