ID A0A2G5B0L9_COERN Unreviewed; 1028 AA.
AC A0A2G5B0L9;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Probable DNA polymerase {ECO:0000256|ARBA:ARBA00014385};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=COEREDRAFT_51915 {ECO:0000313|EMBL:PIA12563.1};
OS Coemansia reversa (strain ATCC 12441 / NRRL 1564).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=763665 {ECO:0000313|EMBL:PIA12563.1, ECO:0000313|Proteomes:UP000242474};
RN [1] {ECO:0000313|EMBL:PIA12563.1, ECO:0000313|Proteomes:UP000242474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1564 {ECO:0000313|EMBL:PIA12563.1,
RC ECO:0000313|Proteomes:UP000242474};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KZ303659; PIA12563.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5B0L9; -.
DR STRING; 763665.A0A2G5B0L9; -.
DR OrthoDB; 1385053at2759; -.
DR Proteomes; UP000242474; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR InterPro; IPR004868; DNA-dir_DNA_pol_B_mt/vir.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR33568; DNA POLYMERASE; 1.
DR PANTHER; PTHR33568:SF3; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF03175; DNA_pol_B_2; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000242474};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 437..902
FT /note="DNA-directed DNA polymerase family B
FT mitochondria/virus"
FT /evidence="ECO:0000259|Pfam:PF03175"
SQ SEQUENCE 1028 AA; 120776 MW; E1B7F959FCB5B57E CRC64;
MSEYEFMRRG MSRIDRSTPS VHTMEITRDE MRLEQTLEYL QLKNELWDKM DKREITADDA
RKQLDEEIGI LKKVMDRRRK RDSKKKVSST RKKVEKDYET LRSKGWDKRN IGMEVIEEKH
LVQTDLISVY IPSESEFMKH SAQMKKAILE RQKNPLEKPE HYCMASVQIC GKNIFVTKTS
LTPVLTPDGD PSPKFFEKLC EKVVECLRRT ENYEERSEDI TCNRVLMTYT ISQWESVRNW
YPDHDGSSTK IFKDFTVFLA PNEKVNCQQQ CVEELNKIYH GENFNVAGVW DPKKKLEAMI
PQKKVITYIP CQGDIRYVKE LDDLMTSYQE NIANTDCKNI ARLIKWNDHM AVITKIKTTR
KRNRVQRRRA INTDISDTLE EEQSNIDIFV DIEAFGKTYE DNYAEQVPYL VCWADGNDIY
NAYGEDCMKE FVDQILNKYD KEITLWAWYG SGYDYQHIYP YLKAKCTYDI CKLRNNSIIY
ARFDFERLKL KIHLKDPYLF ILTSLDKAAK AFGVINKGNF PHTVIEGFDD LNRVLENWIS
EKSRTVSEQG NKIIKIYTET WNEFEKIQNY KTILEKAIEY CTIDVIAMQQ IWKKFSNLVQ
EKLAVEITTE IFTLSQLSMR IMEACLPTSV WLFIPDRPTY EFIHDAIYGG RVIAKNGEYR
EPILYADAVS LYPSAMKLLE HGYGRPIKVN RIEWKRHGIY EVTLIHRSES EPKNYMEFVP
RRIDKKLKWN WFKEHRGVYH TYDLLIAKEE GFDIICHRGI EYSSKGYIFN NYIEQLYKLK
EKHSFCDCAG SSKEKCPIRM VAKIALNGGG YGKFVQKPID TETYIVRRDI IAGECDRLEE
NKNGEIFFGG TLIKRPIFHH LDGNDYDKMI FTHESEPHYS TQNGISILSG SRYRLYKLCK
QFPGMKVIYS DTDSVFIKAN SINIDKFRSS CGTKLGQLDD SIDNTENITI NYMIIGGPKM
YAYEYYDKNG ERKTNMHCKG IPTKMLDINH FKHIIDSEDN TLSYKFAIMK RRIVGVKTDI
IDKTIMQT
//
