ID A0A2G5BCU3_COERN Unreviewed; 383 AA.
AC A0A2G5BCU3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Di-copper centre-containing protein {ECO:0000313|EMBL:PIA16829.1};
GN ORFNames=COEREDRAFT_80895 {ECO:0000313|EMBL:PIA16829.1};
OS Coemansia reversa (strain ATCC 12441 / NRRL 1564).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=763665 {ECO:0000313|EMBL:PIA16829.1, ECO:0000313|Proteomes:UP000242474};
RN [1] {ECO:0000313|EMBL:PIA16829.1, ECO:0000313|Proteomes:UP000242474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1564 {ECO:0000313|EMBL:PIA16829.1,
RC ECO:0000313|Proteomes:UP000242474};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; KZ303497; PIA16829.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5BCU3; -.
DR STRING; 763665.A0A2G5BCU3; -.
DR OrthoDB; 4070889at2759; -.
DR Proteomes; UP000242474; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000242474};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..383
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013888847"
FT DOMAIN 78..95
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
SQ SEQUENCE 383 AA; 43470 MW; 4BC18E5E6DF10371 CRC64;
MKLSAALLSA TAIGLSAVQV INAQQNQPAC SNVYTRKELL SLTSSEWSLY KSILTAMQRD
GWFAWFAYLH NTWFGSIHGQ SQFFPFHRRF VYEWEKVGKQ YNSAFAQPYW DEMRDYRTPA
SSQVLSSNWL GGNGQGNNRC VQNGVQGGWT MTYPNNHCFS RSFSNNGNPN SWYSPEYIES
VIQRSADMTA LRPGIEYSLH GIVHLDIGGD MSQRSSPNDW IFMLHHANID RLWWQWQANR
NHMWTMDGPN TDGSAISLNS NIVYFDEPIR NVMQLGYGQM CYQYGSNPIR RRSLSASATQ
KISSVLPQGV LSEWFPDTAK SPMAIAAIDP AMEKSGRPIP YPGTLTDDWI SKQNLDRAAV
KRVEADARSF VDAMKNAKYN SPY
//
