ID A0A2G5BGY1_COERN Unreviewed; 655 AA.
AC A0A2G5BGY1;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Metallo-hydrolase/oxidoreductase {ECO:0000313|EMBL:PIA18263.1};
GN ORFNames=COEREDRAFT_79776 {ECO:0000313|EMBL:PIA18263.1};
OS Coemansia reversa (strain ATCC 12441 / NRRL 1564).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=763665 {ECO:0000313|EMBL:PIA18263.1, ECO:0000313|Proteomes:UP000242474};
RN [1] {ECO:0000313|EMBL:PIA18263.1, ECO:0000313|Proteomes:UP000242474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1564 {ECO:0000313|EMBL:PIA18263.1,
RC ECO:0000313|Proteomes:UP000242474};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
CC {ECO:0000256|ARBA:ARBA00007093}.
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DR EMBL; KZ303490; PIA18263.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5BGY1; -.
DR STRING; 763665.A0A2G5BGY1; -.
DR OrthoDB; 169081at2759; -.
DR Proteomes; UP000242474; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16291; INTS11-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR041897; INTS11-like_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:PIA18263.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242474}.
FT DOMAIN 13..230
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 242..360
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
FT REGION 463..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 655 AA; 73701 MW; AB400DF97065D4AF CRC64;
MKVVPLGAGQ DVGRSCVLVT LGGKTIMFDC GMHMGYNDER RFPNFNYITT SDDFTSRIDA
VVITHFHLDH CGALPHFSEQ RGYHGPIYMT PPTKAICPIL LEDYRKITVE RKGETGFFTS
QHIKDCMKKV VPLHLHETVW VDDELELRAY YAGHVLGAAM IYARCGSESV VYTGDYNMTP
DRHLGAAWIE KVRPDILITE STYGTTIRDS KRARERDFTE KVRSCVARGG KVLIPCFALG
RAQELCILIE SYWERLGLKV PVYFSAGLTE KANRYYKLFI NWTNQKVKES FVDRNPFDFK
YIKPWNRDYV DLPGPMVLFA TPGMLHIGTS LEVFKKWAPD ERNMLIMPGY CVAGTIGAKV
LSGMKVVDID QYSQVNVNID VQNLSFSAHA DAKGIMELIR QASPRNVVLV HGEKSRMSYL
KSKIMGEFGC PCYDPANGEL LEIETEQDVR ALMSDQLFQR AWSGEQQRQE RLEKDNQIKP
PSPITQMPVR GVLLLGDGGK RLTRLLDPSE FDLDQVPVAE PRAENFKTDD QQPTTSGDTR
SSDEPDEKLE TVVFSTRKIF DDVAVAQRMG LDDNADTIQA VLDAVYELFS IDSAQQVHQH
KNVDGFGSVS VGDSVKVSTS PVSDFDELPS LSVSWAWEEE ELATQTLAIL NRVLG
//
