ID A0A2G5BI30_COERN Unreviewed; 1181 AA.
AC A0A2G5BI30;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Voltage-gated potassium channel {ECO:0000313|EMBL:PIA18670.1};
GN ORFNames=COEREDRAFT_13727 {ECO:0000313|EMBL:PIA18670.1};
OS Coemansia reversa (strain ATCC 12441 / NRRL 1564).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=763665 {ECO:0000313|EMBL:PIA18670.1, ECO:0000313|Proteomes:UP000242474};
RN [1] {ECO:0000313|EMBL:PIA18670.1, ECO:0000313|Proteomes:UP000242474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1564 {ECO:0000313|EMBL:PIA18670.1,
RC ECO:0000313|Proteomes:UP000242474};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|RuleBase:RU003857}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ303489; PIA18670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5BI30; -.
DR STRING; 763665.A0A2G5BI30; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000242474; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF291; POTASSIUM CHANNEL SUBFAMILY K MEMBER 18; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|RuleBase:RU003857, ECO:0000313|EMBL:PIA18670.1};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242474};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 364..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 915..936
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 943..959
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 971..995
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 527..599
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 923..993
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 1..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1070..1089
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1098..1174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 604..631
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..700
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..831
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..860
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1089
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1149
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1181 AA; 131566 MW; 3F52E6ABB5442469 CRC64;
MNRSDENRPD HNQDQDNESG HARGSVYSQS HSHNSSYDYD NSDANNGDGE ASDDNGWTPV
VKFAEMPKSP TGSIRIRASR GWRRRAHSAL GLDNRQQQAE ALPSSAQMHM PASARIRSPR
SRKKRPARIQ SGELSSIRSF PAPHALDAEE GGTHTRRPPP VNVSVATSPA PFTPASAAVS
ENTGLHNRRG SSPHSGRGPL TRMRSSVTPF SAPVTDEVGG GYSVAAPDQH AHPLYSQHDI
SSDESVTPVS RQTNGSSSEL EEIWFQRART FSVMSPSEHA NVIPDADRSS GSVRSLPRVL
TVTSAREKDG GDMETGIDDL PPLRFGREVT NDLRNIQLTF EAPSSSKQRS ANPLKHLIRS
KHNFRALVTY GGYLIPINIL LNVILLDRGW LQYKEVDSEG IHETVNNPIG YLITSVISLI
LIVASGICFI LRCLEFDVLS TTVISIVSNF VNAVLILASA IMYLHNERPK HPDANLTGEY
YVSYAGAVVA LLNALLLLLD IIITPGFRYR GSGMSRQQRI LQFNIIIVVV WIGIGGYAWS
KIEDWDTITS VMFCMVTITT IGFGNISPTK TYSRVLQLLY GPLGILMFGL MLLNTRNVIL
QITRNKFRVA KRDLKAKREK IEQEITSTRV KKRLAARPEH RGWKSIATDM LGRVFLSHNE
RVRVGIPRWL RRRLDEHDDE HDAGGVDLEA GVRRSDSQVG RDRGNPNAFP HSQGDASSPT
ADGSTSAPEQ GMEEHQNITF VDPSTRAHSL HLHDGTVPSH IGNVNREDTV PYPMERTYTT
ASRFSQIRSA LTRPGKMQNI RRRIGMHSRA SESDGRDAKS GTSDDSDSSD GKARPQSTGD
NSDSETGLDA SQTIQPDETV GNSPAKGGRL NKALSIASNM RDRVRGRGQG QDSRRSGKTQ
RHRHKKTRRD ITRQLWVALI INITFWLSSA GLFYAFERKS WSYFDAMWFC YVAFTTIGYG
DITPVTTEGM VTFICLCFIA VGLETFLVVS AVGFFTDVLN ETMKRTRVQK RIARHRKSLA
AYEIRRHIKH PNYNPFSIGD DERMLKIGYR RFKRAMQRVG EILGGKRSIG NTFTRHRTKD
QRERDERLTE GFIRHTTGMG GFASSNWQPP SPSQSFVTPQ PIAQHQTLQS LHASPPHVQE
PTRNSISMPP PDQLRRKEST GESNRSASFS SAPDDILWAF F
//
