ID A0A2G5BIT3_COERN Unreviewed; 1218 AA.
AC A0A2G5BIT3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Beta-adaptin appendage C-terminal subdomain domain-containing protein {ECO:0000259|SMART:SM01020};
GN ORFNames=COEREDRAFT_13494 {ECO:0000313|EMBL:PIA18915.1};
OS Coemansia reversa (strain ATCC 12441 / NRRL 1564).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Kickxellomycetes; Kickxellales; Kickxellaceae; Coemansia.
OX NCBI_TaxID=763665 {ECO:0000313|EMBL:PIA18915.1, ECO:0000313|Proteomes:UP000242474};
RN [1] {ECO:0000313|EMBL:PIA18915.1, ECO:0000313|Proteomes:UP000242474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 1564 {ECO:0000313|EMBL:PIA18915.1,
RC ECO:0000313|Proteomes:UP000242474};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613}.
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DR EMBL; KZ303488; PIA18915.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5BIT3; -.
DR STRING; 763665.A0A2G5BIT3; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000242474; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF13; AP-2 COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000242474};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1105..1216
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 595..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1218 AA; 132917 MW; C8F11F7415725F76 CRC64;
MSDAKFFQRG KVHDLRLELT SEKKDPRHQR KKVAMKKVVA NMTMGNDMSS LFREVIACMG
IPDLEVKKMV YLFLINYARA RAEIANHAVN GFEDDVNDPN PLIRAMAIRT MGYIYVERVL
ESLIDPLRHC LRDRDPYVRK TAAMAVLKLY MFDRSLVEEE RFLDMLKDLL ADGNPAVVAN
AVAALTEVSE RSPHIKLKLN MKIASKLITA LNECNEWGQI YIIESLMYVT PQSSEDAETI
IERIMPRLQH GNSGVVLVCI KVIAYMMNYV AKTETLEPIL RKLSPPLVTL LASGPEVQYI
TLRNIQLLLQ RWPTILQNQL RAFFCKYDDP IYVKLAKLEV ILSLTTEENA RVVLTELVEY
ATEIDVDFVR KAVRSIGRIA IKIELAADRC VRALMDLIQT KVNYVVQEAI VVIRDVFRKY
PNRYEAIIGT LCQNLDTLDE PEARAAMVWI IGQYADRIEN SDEVLGKFLE TFLDDPAEVQ
LALLTAIVKL FIMRPTAGQD LVPKVLKWAT EEIDSPDIRD RGFIYWRLLS TDPEMARTVV
LSEKPEISAE GERLEMPLLE ELLLQVGSLS SIYRKPPSSF IPFAKKRVLG QSPALSRLTI
APPPMSRLPR TNTVPKGQVA TKHQSGGSGQ ADSQQSGLPR SNSAQMSSSM LDVTNQAGLS
NPYLNDVTPG FMSNNDAVLI DLMSMDYNDD PSASNMAVNS GGMLGFNGNF GSSGMNIPNM
DMPFNNNSSS GSAKDIAVGS QTNAAFSGAG TASTSASVAP DSQMFNSAFD AAGLDALSNM
PTSASSLSAA RATSNRSPVP DLVRQFTSTF ELSALGSAAS GNSSQPADSH QQQQLFSPPG
STPTSISPFG PSAFPTALSS KSNTYPAGNS SNNTSNIFDV SSSFATPTSA NSLLNSNSFA
AVSGTAAGTT SVTALDFLLP TTTTTALTTT TAPLAASATF DAGNSSLIQQ EVNDLATKMY
NTGMLNSFQT QTTGDSGAVA SSSSAPYVPA RRVLLDAQQT QGLEILGTFA RRQGQIQMDL
SLANRNNIPI GDFAIQFNKN TFGIMPGAPL ALGTLGAMCS MEVSIPLAMG GPSMVMQPLT
NIQIAFKCTM GIFYFQTQFS LHILLDENGQ SDQGTFLRMW KAIPETMQGS TSMQSLRFTS
MEDMRDKLNM NNVFTVAQRS IAGATHFYTS SKLCDGTIFY SEIKVSEDFR AAVITTKSNN
VQAIVLYQEA INGICTAM
//
