ID   A0A2G5C812_AQUCA        Unreviewed;       535 AA.
AC   A0A2G5C812;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Deoxynucleoside kinase domain-containing protein {ECO:0000259|Pfam:PF01712};
GN   ORFNames=AQUCO_07800048v1 {ECO:0000313|EMBL:PIA27433.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA27433.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA27433.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305095; PIA27433.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5C812; -.
DR   STRING; 218851.A0A2G5C812; -.
DR   InParanoid; A0A2G5C812; -.
DR   OrthoDB; 1199760at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   CDD; cd01673; dNK; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR031314; DNK_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR   PANTHER; PTHR10513:SF35; THYMIDINE KINASE 2, MITOCHONDRIAL; 1.
DR   Pfam; PF01712; dNK; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          277..468
FT                   /note="Deoxynucleoside kinase"
FT                   /evidence="ECO:0000259|Pfam:PF01712"
FT   REGION          137..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        149..164
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..182
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  60482 MW;  3A581850A96736B7 CRC64;
     MQKLLRSSSV VGSSSCSSTN PILCTFGAPT IISTKFHTNI KFPFQMPPTT TPTPTPNITS
     FYSKKKSITT PPRSLLSVSL TTSSINCSSC RCSFDVTVTN RVRAWAGFRE NWSRSAWFNT
     KSDGGFQGIL VEGSSGVKNL ETESGEESDC EDNKDKEKPL RLHRRNRGSS SGNASSGSGL
     PGNPDLLTIP GVGPRNLRKL VDKGIGEVAD LKQLYKDKFF GTSSQKMVEF LQSSVGIIHK
     NHAESITSYI EKTVDEELKE DNPNSDTKPS QKKRLTFCVE GNISVGKSTF LQRIANETLE
     LRDLVEVVPE PISKWQDIGP DHFNILDAFY AEPQRYAYTF QNYVFVTRVM QEQESSGGVK
     PLRLMERSVF SDRMVFVRAV HEAKWMNEME ISIYDSWFDP VVSNLPGLIP DGFIYLRASP
     DTCHKRMMLR KREEEGGVTL NYLRDLHEKH ESWLFPFESG NHGVLSVNQL PLKMDNPLHP
     EIRDRVFYLE GDHLHSSIKK VFFFYHSCTY HSRLNLICLL LWPGSCFGFG LRTQH
//