ID   A0A2G5CE55_AQUCA        Unreviewed;       523 AA.
AC   A0A2G5CE55;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   13-SEP-2023, entry version 21.
DE   RecName: Full=PDZ domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=AQUCO_05800005v1 {ECO:0000313|EMBL:PIA29565.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA29565.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA29565.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S1C family.
CC       {ECO:0000256|ARBA:ARBA00010541}.
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DR   EMBL; KZ305075; PIA29565.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5CE55; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd00987; PDZ_serine_protease; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 3.20.190.20; -; 1.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR041517; DEGP_PDZ.
DR   InterPro; IPR046449; DEGP_PDZ_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   PANTHER; PTHR45980; -; 1.
DR   PANTHER; PTHR45980:SF9; PROTEASE DO-LIKE 10, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF13180; PDZ_2; 1.
DR   Pfam; PF17815; PDZ_3; 1.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          344..444
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|Pfam:PF13180"
FT   DOMAIN          451..514
FT                   /note="Protease Do-like PDZ"
FT                   /evidence="ECO:0000259|Pfam:PF17815"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..31
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PIA29565.1"
SQ   SEQUENCE   523 AA;  57508 MW;  243032A71F14BCCF CRC64;
     GGGGGGGAAA ITAASKGKEK EKEKEKEKEK ERVRMLTLLR TVAKIRSSSS SSSSSCLLRH
     RPLATSLVRN GVISNRTSED GGLWLFSTFS PTFYHSTTIS NQVELEVEVE VEVEVEDSGI
     IPPPPSPPYE YGGAIEVALD SVVKIFTVAS SPNYFLPWQN KSQRETMGSG FVLSGRRILT
     NAHVVADHTF VLVRKHGSPN KYRAHVHAIG HECDLAILHV DDPDFWNGMT SLHLGHIPFL
     QQAVAVVGYP QGGDNISVTK GVVSRVEPTQ YVHGATQLMA IQIDAAINPG NSGGPAIMGD
     KVAGVAFQNL SGAENIGYII PVPVIKHFIS GVEECGKYVG FCSLGLSCQP TENVQLREYF
     RMGNEMTGVL VSKINPLSDA HRILKKDDII LAFDGVPIAN DGTVPFRNRE RITFDHLVSM
     KKPNETAKIR VLRDGIQYEF TVTLQPLQPL VPVHQFDKLP SYFIFAGFVF IPLTQPYLHE
     YGEDWYNTSP RRLCERALRE LPSKAGEQFV ILSQGMSVFQ NHR
//