ID   A0A2G5CIC6_AQUCA        Unreviewed;       918 AA.
AC   A0A2G5CIC6;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AQUCO_05500128v1 {ECO:0000313|EMBL:PIA30597.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA30597.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA30597.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305072; PIA30597.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5CIC6; -.
DR   STRING; 218851.A0A2G5CIC6; -.
DR   InParanoid; A0A2G5CIC6; -.
DR   OrthoDB; 646988at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1185; DISEASE RESISTANCE RPP8-LIKE PROTEIN 3-RELATED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          13..99
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          180..413
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   918 AA;  105609 MW;  D40437F13C0CF990 CRC64;
     MAEAFVLSAA SAIVASVVKS LGKLVIDQTI AFGTSFREVH EQFKSLMDEL ESIQGFLHTA
     DSNHNQDPGI RIWVSDVREI AYDVDDVIDA FLRKVPYKED GESSFMRYAR KPKKILNSYK
     IGKEMETIFS KLKDISKRQK RYAGITIQQT MPSTSSNTNN MLLRRVYSHT KDDATVGLEE
     HTKTLVSELL KEEDRLCVVS IYGMGGLGKT TLAKEVYNHR NIKNHFHRYA WTSISQQMST
     KEVLKEILRK VSTLNSKDMG EMNEVELVGN LFRFLGGKRY LIVLDDIWNT TDWDILKPAF
     PNSRGSKVML STRKLEVARH ADPMSFHLNP RFLTDDEGWE LLCRKALIPL SNDLEECGRR
     MVKKCGGLPL AIIVLGGMLQ SKRSLGEWEN VSKKIGISGH ESRVLSILSL SYEELPYHLK
     PLFLYLGLFP EDSNIRVKKL VRMWMAERLI TEQEGETIEE LGRQCLDELI HRCMVQIGKK
     RLGEERAKTC RLHDKMRDLC IEIGKKENFF KVMSHQNNDP SSSSSSVFLK LRRCAIHVEE
     KGKQYIFPKH LTPCLRTAIF IPKDLSTEYC PNIVYKDFKS LKVLEFQGEL KPEKELCGVV
     RKLSNLRYLS VRGLAFEFGN LIGNFVCLET LDLRNCHIDE SMCKVISSFM PQLRHFYGWK
     IQLSKINKMR KLQTLYKGWA GPWITDLVKL TNLDKLGIVI LDEKSIRLFT NVIVGGGGLD
     KLRSLYLHTK IEFPSDLLEY LSEKIHLMKL RLDGKFKNGK LPSLFPSNLI KLHLGFTNLS
     EDPMPTLEKL PHLLFLMLHG SYLSKEMVCS AKGFPKLQNL QILNFDQLEE WTVEEGAMPC
     LTKCWICVCK KLKMVPQGFK FLTMLQELEI FEMPKSFEQR VKEGGEDWPT VQHIPSIIIF
     NYRGEEREEE RGQNSQTI
//