ID   A0A2G5CQK0_AQUCA        Unreviewed;       572 AA.
AC   A0A2G5CQK0;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Auxin efflux carrier component {ECO:0000256|RuleBase:RU362108};
GN   ORFNames=AQUCO_04100165v1 {ECO:0000313|EMBL:PIA33538.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA33538.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA33538.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC       {ECO:0000256|RuleBase:RU362108}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362108}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362108}.
CC   -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC       {ECO:0000256|ARBA:ARBA00009177, ECO:0000256|RuleBase:RU362108}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362108}.
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DR   EMBL; KZ305058; PIA33538.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5CQK0; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-UniRule.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR014024; Auxin_eff_plant.
DR   InterPro; IPR004776; Mem_transp_PIN-like.
DR   NCBIfam; TIGR00946; 2a69; 1.
DR   PANTHER; PTHR31752; AUXIN EFFLUX CARRIER COMPONENT 1B-RELATED; 1.
DR   PANTHER; PTHR31752:SF18; AUXIN EFFLUX CARRIER COMPONENT 4; 1.
DR   Pfam; PF03547; Mem_trans; 1.
PE   3: Inferred from homology;
KW   Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294,
KW   ECO:0000256|RuleBase:RU362108};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362108};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362108};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362108}; Transport {ECO:0000256|RuleBase:RU362108}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        40..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        71..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        102..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        510..528
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   TRANSMEM        548..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362108"
FT   REGION          328..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          444..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..475
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   572 AA;  63675 MW;  706546DCB6BCE621 CRC64;
     MISWKDLYTV LTAVVPLYVA MILAYGSVRW WKIFTPDQCS GINRFVAVFA VPLLSFHFIS
     TNDPYAMNFR FIAADTLQKI IMLVVLGIWT KFSEHGNLEW MITIFSLSTL PNTLVMGIPL
     LIAMYGDFSG SLMVQVVVLQ CIIWYTLLLF LFEYRGAKML IMEQFPETAA SIVSFKIDSD
     VMSLDGRDFL QTDAEIGNDG KLHVTVRKSN ASRRSLGPCS LSGLTPRPSN LTGAEIYSLS
     SSRNPTPRAS NFNNSDFYSM MGCQGLQGRQ SNFGTTDLYS VQSSRGPTPR PSNFEETCAP
     GSGVQAVNSS RFGIHPAPPV TNSYPMPNPE ISNTGAKVQK SQPQQQLQQG QIQSQTKTTH
     DAKELHMFVW SASTSPVSEG GGLHVFGGTD YGASDQSGRS DQGAKEIRML VTDHPQNGEA
     KEATPENEDF ATEDFSFMGS REMMDEGDEE RDKNSGPNGL SKLGSSSTSE LHPKTGAMSD
     SGAGKQMPPA SVMSRLILIM VWRKLIRNPN TYSSLIGLIW SLVAFRIHRW EHLNLKENRS
     ENVWLKEYPT LLCIFLLLRS NFLHLFYVFF PW
//