ID A0A2G5CT22_AQUCA Unreviewed; 866 AA.
AC A0A2G5CT22;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AQUCO_03900129v1 {ECO:0000313|EMBL:PIA34017.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA34017.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA34017.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ305056; PIA34017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5CT22; -.
DR STRING; 218851.A0A2G5CT22; -.
DR InParanoid; A0A2G5CT22; -.
DR OrthoDB; 759159at2759; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1185; DISEASE RESISTANCE RPP8-LIKE PROTEIN 3-RELATED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT DOMAIN 5..84
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 164..408
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 866 AA; 99613 MW; C2AC34EAF92EA5A5 CRC64;
MAEAVISVVV ERLANLLIGE IFFLKGVRAE FERLQKELVS IQGFLKTVDS IHNQDPSFRI
WVADVRDVAY DVEDIIDNFL LAEEGINNFF KRCARKLRNI FKLHRSGVDL KEIFAKLDDI
SERRKRYDTT NVRERTIASN TSDLLLRRSY PHQRDDDIIG LEVEKNRLMA ELSKEEDRLC
VVSIYGMGGS GKTTLAKEVY NHQNIKDHFD SYAWTSISRQ MNARAVLQEI LRKVGNTPSL
ETGSMQEVEL VEKIHAILEG KRYLVVLDDI WNTKDWDVLE PAFPKRKGSK IMFTTRIKEV
AEHADRWSYH CEPQSLTDDE AWELLCKKAF PPNVADSRCF FSSDKEKCGR AMVKKCGGLP
LAIVVLGGLL ASKRSLDEWE TVSKQIETIG MRNGKDDDVV LSILSLSYIE LPYHLKPLFI
YLGLFPEDSN IAVKKVVHMW IAENLIIGQD GETIEEVGRH YLDELIHRCM VQIGQKSLGG
ERVKTCRLHD KMRDLSIDIG KKENFFEVIS HQSIKPSSSS APCSKLRRCS IYIEEKGKEY
LFPKHLTPCL RTVFFNVNGY FPNINIVYKD FKLLKVLEIQ EGGDYSLEFY EALMKLRNLR
YLRVAGLFIL SSNVMHQLRH VYGREIVLSK INKMTELQSL RYVYGGSWMT DLLKLTNLEK
LGIRNLNANT SRLLTIAIGG GLDKLRSLTV LRGDELSSNL LEAISMKHHL QKLSLQGEVK
KFPSQFPSNL IKLVLDLDIS YNLLEDPMPT LEKLLHLLSL ELWYSYYGKQ MVCSAKGFPK
LKHLKICYFH PLEEWTVEKG AMTCLTTCAI CYCEKLKMVP QGFRFLTRLQ ELKIIHMPES
FEERVKEGGE DWETVKHIPS ITTVKN
//
