ID   A0A2G5D0S9_AQUCA        Unreviewed;       915 AA.
AC   A0A2G5D0S9;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE            EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
DE   Flags: Fragment;
GN   ORFNames=AQUCO_03100103v1 {ECO:0000313|EMBL:PIA37121.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA37121.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA37121.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU363044};
CC   -!- SIMILARITY: Belongs to the helicase family.
CC       {ECO:0000256|RuleBase:RU363044}.
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DR   EMBL; KZ305048; PIA37121.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5D0S9; -.
DR   STRING; 218851.A0A2G5D0S9; -.
DR   InParanoid; A0A2G5D0S9; -.
DR   OrthoDB; 1366201at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR010285; DNA_helicase_pif1-like.
DR   InterPro; IPR025476; Helitron_helicase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR   PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR   Pfam; PF14214; Helitron_like_N; 1.
DR   Pfam; PF05970; PIF1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU363044};
KW   DNA damage {ECO:0000256|RuleBase:RU363044};
KW   DNA recombination {ECO:0000256|RuleBase:RU363044};
KW   DNA repair {ECO:0000256|RuleBase:RU363044};
KW   Helicase {ECO:0000256|RuleBase:RU363044};
KW   Hydrolase {ECO:0000256|RuleBase:RU363044};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          150..258
FT                   /note="Helitron helicase-like"
FT                   /evidence="ECO:0000259|Pfam:PF14214"
FT   NON_TER         915
FT                   /evidence="ECO:0000313|EMBL:PIA37121.1"
SQ   SEQUENCE   915 AA;  104666 MW;  CA62591D01D31F21 CRC64;
     MEGNDCTTVV HPKRNLHLNP AILEIIQETL LESNELCKIY KGAYDVLKSA NSNGGESIPI
     RLAYTPTTDP RRYNLPTSED IAVIIPGDET EPTSKRDIIP HLKNNNLERI SECHPLYLPS
     HYILLFLTGD LGWSTDMKHW DVKNERYFTV TDIVTNGHNP NDIGKKFILS STHLGSPWHM
     YEIYQDSMAI TRYYKHPDIF MTVTSNPKWP EIQIELKPGQ AALDRPDLVA RVFELKRKAI
     MHEIESKRLF GRVVAKVTTD QVDRIVSAEF PDPIKHPPLF ETIKKCMVHV CMENKVCKSR
     YPRENVNDNR IDVDGYPIYR RRKTGKKMFD CHINVEICAS VRTVKYIHKY IYKGHDRTTM
     VVGAEDDEIQ QYLDARYVGP TEAAWRLYGF RIHEELPCVT RLALHRKGMH VCVFNPNDTP
     EQYEKNPTTK AYTYQQFPEH FRWCKDNKKW TPRVTSAFSI GRMYFANPNS GERFYLRLLL
     TVVKGPSSFE SLYSVDGIEH KTYREACIAR GLLEDDNEWD KCLEEAVIMK SDPSDSDVCD
     YGLFLMNDYL LESGKTLSDF PNMPLLCKTW NEVVTNRLIT EHQNFVYQGL YEKAQEKVAR
     FNTEQLNAYT EITNSVRNDS GQVFFLSGPA GTGKTFVYNT VADTLRSEGH IVIMVASSRI
     ASLLLTGGRT THSTFKIPFE VLDDSVCSVT KQTIHAELFK RAKLIIWDEV PMQHRFCVEA
     VDCTLRDIRE IKEPFGGVTV VLGGDFKQTL PVITKGTRQE IVRACLTKSH LWSGVRLLTL
     VNNMRLNSND TENIGTNPKE DVELPSEIKR CKSTMDLLFK VYPNLNVGEV ATKTYLHERS
     ILSARNDDVA TLNELAINHS PGELHEYLAA DKTIEDDQPI ENRGNSISNE NMQALDPPSL
     PPFKLQLKVG CPIML
//