ID   A0A2G5D6I3_AQUCA        Unreviewed;       252 AA.
AC   A0A2G5D6I3;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=MBD domain-containing protein {ECO:0000259|PROSITE:PS50982};
GN   ORFNames=AQUCO_02700363v1 {ECO:0000313|EMBL:PIA39125.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA39125.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA39125.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KZ305044; PIA39125.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5D6I3; -.
DR   STRING; 218851.A0A2G5D6I3; -.
DR   InParanoid; A0A2G5D6I3; -.
DR   OrthoDB; 829814at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00122; MBD; 1.
DR   InterPro; IPR016177; DNA-bd_dom_sf.
DR   InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR   PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR   PANTHER; PTHR12396:SF46; METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 6; 1.
DR   Pfam; PF01429; MBD; 1.
DR   SUPFAM; SSF54171; DNA-binding domain; 1.
DR   PROSITE; PS50982; MBD; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          112..185
FT                   /note="MBD"
FT                   /evidence="ECO:0000259|PROSITE:PS50982"
FT   REGION          71..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   252 AA;  28423 MW;  A21CEE9A793F1154 CRC64;
     MAIPNITTDL DLKLAASSAS TTPSTPKFSK IGSLSSPLTP LNRFNNLVNS TAPVSLNYEQ
     LLVSESEIKT PSCSSLPLPL PPIPKPISKQ ELTQSGTGSR SSRKRRKGME EFLDPEKNPE
     WLPPGWKVEV RVRDNGKSAG SKDTYYREPI KGRKFRSKRE VLEFVENDGH VLRSHKRLKT
     KKEESPNPLP AKSSQARPYD YFSDEPPEKV RWVLGDSGDS WIPFIGDEMV PEHVRLQWAA
     MFNPLYGSKY QR
//