ID   A0A2G5D9M6_AQUCA        Unreviewed;       740 AA.
AC   A0A2G5D9M6;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=TTF-type domain-containing protein {ECO:0000259|SMART:SM00597};
GN   ORFNames=AQUCO_02500131v1 {ECO:0000313|EMBL:PIA40218.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA40218.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA40218.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305042; PIA40218.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5D9M6; -.
DR   STRING; 218851.A0A2G5D9M6; -.
DR   InParanoid; A0A2G5D9M6; -.
DR   OrthoDB; 890680at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR025398; DUF4371.
DR   InterPro; IPR008906; HATC_C_dom.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR006580; Znf_TTF.
DR   PANTHER; PTHR11697; GENERAL TRANSCRIPTION FACTOR 2-RELATED ZINC FINGER PROTEIN; 1.
DR   PANTHER; PTHR11697:SF230; ZINC FINGER, MYM DOMAIN-CONTAINING 1; 1.
DR   Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR   Pfam; PF14291; DUF4371; 1.
DR   SMART; SM00597; ZnF_TTF; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        674..696
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          70..165
FT                   /note="TTF-type"
FT                   /evidence="ECO:0000259|SMART:SM00597"
SQ   SEQUENCE   740 AA;  84788 MW;  4AB44F2F577EBF67 CRC64;
     MERYFQKKSV INSNPPSYID LSNLPTDPGL RKKNSEYPSN VRDNVRRAYL LNGPYQPDIE
     FPQTKGNEDE NQKFVIDWYK EFTWIEYSIK RDAAFCLYCY LFKPESRNRS QGAGDAFMAT
     GFKNWKKKQG LRDHVGGPSS AHNQAYRKGQ DLLNQSQDIE TVLQRQSSQA RSEYRVRLKA
     SVDCVHFLLK QGLAFRGHNE TTNSNNRGNF LELLEFSAFL NKDIKDVVLQ NAPENNKLTA
     HVVQKDIVNS FAVETTNVIL KELGDAFFFV LIDESRDISV KEQMDVVIRF VDDKGCVIER
     FWGFVHVRET TALSLKATLE ELFSKHGLSI GRLCGQGYDG ASNMRGQFGG LKTLIMNENE
     SAYYVHCFAH QLQLALVGVA KNHPRIALLF NLTSNALNIV GVSCKKHASK VIQKIQSGDI
     LSGQGLNQET ALKRSGDTRW GSHYGTLVSF ILMHSSVIDV LEVVMENALT SEQRGEACAL
     LDQMQSFEFI FNLHLMKDIL GITSELSKAL QREDQEIVNV ITLVKVAKQR LNAMRNDGWD
     SFFAEVSSFC VKNDIIIPNM DDPFVERGRS RRRVEVLTNQ HYYRVQLFIR CIDLQNQELE
     NRFNEVNTKL LLCMACLSPR DLFVAFDKEK LIRLAQFYPR DFSSKSLMLL SNQLETYILD
     VRFSNTRKNT VYPLVYMLMT LALILPVATA GVERAFSAMN IIKNKLRNRM ADDWMNDILV
     TYIEKDICET IDDETIMQRF
//