ID A0A2G5DBP0_AQUCA Unreviewed; 790 AA.
AC A0A2G5DBP0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=AQUCO_02300015v1 {ECO:0000313|EMBL:PIA40949.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA40949.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA40949.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ305040; PIA40949.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5DBP0; -.
DR STRING; 218851.A0A2G5DBP0; -.
DR InParanoid; A0A2G5DBP0; -.
DR OrthoDB; 404991at2759; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR044815; CCR1-4.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR46146; SERINE/THREONINE-PROTEIN KINASE-LIKE PROTEIN CCR4; 1.
DR PANTHER; PTHR46146:SF4; SERINE_THREONINE-PROTEIN KINASE-LIKE PROTEIN CCR4; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13540; RCC1_2; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 355..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 447..734
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 329..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 475
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 790 AA; 86497 MW; 918EC50E48B2E85A CRC64;
MHDLAYKLSV VLAKTSNNTI ICALIPSHTR PASFLNCTSF PTTINQIIPI TTFPNISASA
VVGGNGFQCF LRLPATSSVA TLNCLRFSSS TSFNSTYKRI YIGPMLQELD AGNSHICGRV
SRTNSLQCWQ WPEFNTSIGQ SLSEITVGGE FICGLSEFGA IKCFGNDTSI VRSIPTGNFS
LVEAGLTHAC GISLDGNISC WGNGVGNKPA GMFTSLALGD NRSCALRSNR SVVCWGENDF
KLPENLAGIQ FLSIKGKGRI FCGVVASNYS LFCFGSERIN SNSTVFDHVL PGPCRINCPC
GTLEGSGSYC NNNEAICKSC ELAVPPNASP PALPPPPPPP PPSPPPSNRI GRTRIAFLVV
GSVGSSALVI VLCFFLFRFC KTRRCRIHDS GRLDAVAAAH ENESSRRQST RRPTTPEKRL
SHMFSLGNGG QLEEFPLQVL LQATKNFSQD YKIGYGSFGS VYRATLDDGR EVAIKRAEFT
SSLYGIGTKR QDDKENAFIS ELAHLSRVNH KNLVRLYGFC EDVNELVLVY EFMSNGTLHD
HLHKLEDTPL KSWTTRLKVA LDAARGIEYL HTYIVPSIIH RDIKSSNILL DSQWTAKVSD
FGLSLMGPAD NESHLSLRAA GTVGYMDPEY YRLQQLTTKS DVYSFGVVLL ELLSGYKAIH
PHENGAPRNV VDFIVPYITS DALHRVLDPT LPPPTPYEIE AVTFIGYLAA DCVSLEGRDR
PSMTETVNSL ERALAAYKLG LVRHSDSTGS VKMSRFHMEN TFYTCVISIH TPETWGGERT
ETLLTILSID
//
