ID   A0A2G5DWV6_AQUCA        Unreviewed;       471 AA.
AC   A0A2G5DWV6;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0000259|PROSITE:PS51384};
GN   ORFNames=AQUCO_01400521v1 {ECO:0000313|EMBL:PIA47981.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA47981.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA47981.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305031; PIA47979.1; -; Genomic_DNA.
DR   EMBL; KZ305031; PIA47981.1; -; Genomic_DNA.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 2.
DR   InterPro; IPR013112; FAD-bd_8.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR013121; Fe_red_NAD-bd_6.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   PANTHER; PTHR11972:SF41; FERRIC REDUCTION OXIDASE 2; 1.
DR   PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR   Pfam; PF08022; FAD_binding_8; 1.
DR   Pfam; PF08030; NAD_binding_6; 1.
DR   SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR   SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        48..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        308..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          85..190
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   471 AA;  53026 MW;  FA83BC1BA2BC6125 CRC64;
     MQTLKWDKIW ISNVAGELSL LFGLGMWVTS FARIRRQMFE LFFYTHNLYT LFLIFFVLHI
     GISYSFIMMP GLYLFLIDRY LRFLQSRQKV CVLSSLLLPC ETLELNFSKN TGLEYSPTSI
     IFINVPSISK LQWHPFTITS NSNLEPETLS VVIGRGGSWS QKLYQMLSTP SSVERLEVAV
     EGPYGPASTH FLRHDSLVMV SGGLGITPFF SIIRELIFQS TTLGTKTPQI LLICAFRNSA
     DLTMLDFILP GYGTLIDSCP VKLQIEAYVT REKHPPMSTA DKDLIRKISF KPNVLDMPIS
     AILGPNSWLW LGVIISCSFV LFIVMLGIIT RFYIYPIDHN TNMIYPLSSR AVIGMLLICG
     SITLTASAVV VMNKKQNANK ARQNTQFIDA PSPGFHSTDR ELESFPKQSF IQATNVHYGS
     RPDLEMILSK CEGSSIGVLV CGPRKMRHDV ATICSSGLVD NLHFETISFS W
//