ID   A0A2G5E3P5_AQUCA        Unreviewed;       426 AA.
AC   A0A2G5E3P5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN   ORFNames=AQUCO_01300860v1 {ECO:0000313|EMBL:PIA50408.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA50408.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA50408.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR   EMBL; KZ305030; PIA50408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5E3P5; -.
DR   STRING; 218851.A0A2G5E3P5; -.
DR   InParanoid; A0A2G5E3P5; -.
DR   OrthoDB; 1010489at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   PANTHER; PTHR13748:SF40; OS04G0599700 PROTEIN; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          330..425
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   426 AA;  47255 MW;  93B47DF34D8B2C7F CRC64;
     MAKLLLARRT LKTLNETLFK PSINSPFVST FPISQFPRTL HSLVSIPNNA IRPFNTRNMV
     TQSKSRYQEA SRAEAVLETA VDVDNRVPAT VLTGFLGSGK TTLLNHILTS QHGKRIAVIE
     NEFGEVDIDG SLVASHSAVP DDIVMVNNGC LCCTVRGDLV KMLLKLAKEK KDKFDHIVIE
     TTGLAKPAPV IETFSTDELV AKYVKLDGVV TLVDCKHAMH HLNEVKPRFV VNEAVEQVAY
     ADRIILNKVD LVSDLELEAL RKKIMDINGM AHIKEAKFGA VDMDFVLGVG GYDLDRIESE
     VHVDVSVTDN HQHKAGHDHH KHSHSHDSAV SSVSIVCEGV LDLEEVDDWL DRLIEEKGED
     LYRMKGILSV NSSDERRYVF QGVHSTLDGS PGKKWGPDEK RVNKLVFIGR NLDEAALRNG
     LKGCFV
//