ID A0A2G5E4X3_AQUCA Unreviewed; 273 AA.
AC A0A2G5E4X3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
GN ORFNames=AQUCO_01200215v1 {ECO:0000313|EMBL:PIA50804.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA50804.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA50804.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000256|RuleBase:RU910715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU910715};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU910715}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR EMBL; KZ305029; PIA50804.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5E4X3; -.
DR InParanoid; A0A2G5E4X3; -.
DR OrthoDB; 73377at2759; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791:SF28; BIDIRECTIONAL SUGAR TRANSPORTER SWEET3; 1.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU910715};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 97..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 191..212
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 218..239
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT REGION 247..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 273 AA; 30109 MW; CB34CBD2078B28AD CRC64;
MEQASLNSIF YSTKLDLGCS SCLVSTETAQ LIRNVVGIFG NVVNLLLYVT PILTFKRVIK
NKSTEEFSVV PYVAALLNSV LYTLYGSPLA SVGWENVHVF TINAIGCFME TAFIAIYFWY
ATPTKKITVT FIMVPVIVFS SSMLAMSTML NDHHLRHTIL GSFGFFASAS MYGSPLVAVK
QVIATKSVEF MPLNLSLFSF LTSFAWMTYA LLGNDILLAS PNFIGVPLGI LQLVVYAIYS
KYKGTSEETN KGDLEKQEEA DLTTPLITNN ESN
//
