ID   A0A2G5E6J0_AQUCA        Unreviewed;       513 AA.
AC   A0A2G5E6J0;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=4-coumarate--CoA ligase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AQUCO_01100266v1 {ECO:0000313|EMBL:PIA51311.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA51311.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA51311.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305028; PIA51311.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5E6J0; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   CDD; cd05904; 4CL; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24096:SF251; 4-COUMARATE--COA LIGASE-LIKE 9; 1.
DR   PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          54..399
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          451..503
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   513 AA;  56164 MW;  CC6D56A055FAA0AC CRC64;
     MAEINPSSGF CYKTKIYHNL RPQVQLPSTN QPLSASEYAI SLLRSSSLSL ENTISFIDSS
     TDSRLSYSDF IKQVESLSFS LHNRFGLKTG DSAFILSPPS LQISILYFSL LSLGVIISPA
     NPISTIPEIS RQISLSKPVI GFATNVTSSK LPSFLHGTIL IDSDDFKSML TIQPGRVNVR
     VNQTDTAAIL YSSGTTGKVK GVELSHRNII ALTAGFDKVR MEPVEENPPH PIALFTIPLF
     HVFGFFMTIR AVALGETVVL MERFDFVGML KAIETYKVTY VPVSPPLVVA MAKLDVVEKF
     DLSSLTVVGC GGAPLGKEVS EKFLSRFPNV QITQGYGMTE TTGGSYEDVR AEETKKHGSV
     GRLSENMEAK IVDPDTGEAL PPGQRGELWL RGPIVMKGYV GDNEATVATF DSEGWLKTGD
     LCYIDNDGFL YIVDRLKELI KYKAYQVPPA ELEQLLQSHP EIADVAVVPY PDEEAGQIPM
     AFVVRKPGSN LSGTEVMDFV AKQAFLLPNG HYI
//