ID A0A2G5EDX5_AQUCA Unreviewed; 609 AA.
AC A0A2G5EDX5;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AQUCO_00900498v1 {ECO:0000313|EMBL:PIA53959.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA53959.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA53959.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KZ305026; PIA53959.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5EDX5; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 2.
DR Pfam; PF18808; Importin_rep_4; 1.
DR SMART; SM00913; IBN_N; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 42..114
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00913"
FT DOMAIN 368..601
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 419..457
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 609 AA; 66991 MW; 35AE3A89C8D49BBC CRC64;
MDSDSTQLQQ AQLAAILGPD PSSFETLVSH LMSSGNEQRS QAEVLFNLCK QNHPDALSLK
LVHLLESSSH VEIRAMSAIL LRKQLTRDDS YIWPRLSPST QTALKSHLLV CVQREDTKSI
TKKLCDTVSE LASGILPDGG WPELLPFMFQ CVTSDSPKLQ ESALLMFAQL SQYIGETLIP
HLNTLHSVFF QCLSSSSNAD VRIASLGASI NFIQCLSSAS DRDKFQDLLP SMMQTLTEAL
NSGQESIAQE ALELLIELAG TEPKFLRRQL VDVVGSMLQI AEAESLEEGT RHLAIEFVIT
LAEARERAPG MMRKLPQFIS RLFAILMKML LDIEDDAAWH TADSEDEDAG ESSNYSVGQE
CLDRLSISLG GNTIVPVASE VLPAYLAAPE WQKHHAALIA LAQIAEGCSK VMTKNLEQVV
IMVLNSFQDP HPRVRWAAIN AVGQLSTDLG PDLQVQYHQQ VLPALALAMD DFQNPRVQAH
AASAVLNFSE NCTPDILTPY LDGIVSKLLV LLQNGKQMVQ EGALTALASV ADSSQEHFQK
YYDSVMPYLK AILMNATDKS NRMLRAKSME CISLVGMAVG KDKFRDDAKQ VLRTVSLCCT
LIIIIDILL
//
