ID   A0A2G5EF93_AQUCA        Unreviewed;       536 AA.
AC   A0A2G5EF93;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN   ORFNames=AQUCO_00900753v1 {ECO:0000313|EMBL:PIA54413.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA54413.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA54413.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion
CC       cotransporter (TC 2.A.1.14) family. {ECO:0000256|ARBA:ARBA00024362}.
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DR   EMBL; KZ305026; PIA54413.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5EF93; -.
DR   STRING; 218851.A0A2G5EF93; -.
DR   InParanoid; A0A2G5EF93; -.
DR   OrthoDB; 35788at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd17380; MFS_SLC17A9_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR044777; SLC17A9-like.
DR   PANTHER; PTHR11662:SF424; ANION TRANSPORTER 4, CHLOROPLASTIC-RELATED; 1.
DR   PANTHER; PTHR11662; SOLUTE CARRIER FAMILY 17; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        148..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        342..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        382..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        415..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        472..496
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        502..523
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          111..528
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
SQ   SEQUENCE   536 AA;  58903 MW;  37BB33C871358EDD CRC64;
     MTLRLIPDQF LHHFPSSNLK NPKKFKKISK ISSNFSKLHE IKTSKQLPSS TSLLHNRVVN
     DEFIKNRFHS IRTRVSGNDA QSFRAESSLS EETEFRTPSF LEFITSERVK VVSMVGLALA
     LCNADRVVMS VAIVPLSLVH GWSRSFSGIV QSSFLWGYLL SPIAGGALVD YYGGKVVMAW
     GVALWSMATF LTPWAAETSL LVLLAMRVLL GIAEGVALPS MNNMISRWFP QTERSRAVGI
     AMGGFQLGNV IGLTLAPILM SRGGIFGPFV IFGLSGMLWV LVWVSATSST PSRHPQISKY
     ELEYILNKGQ KSVLPSIEKK KRPKTDKVIP PFRRLLSKAP TWALISANAM HSWGYFVILS
     WMPIYFNTIY HVDLRQAAWF SAVPWTMMAV LGYFAGVLSD MLIQNGTDVT LTRKIMQSIG
     FLGPAVALLG LIAAKTPAIA SAWLAVAVGL KSFSHSGFLV NFQEIAPQYA GVLHGMSNTA
     GTFAAIIGTV GAGFFVEMIG SFRGFLLLTS FLYFLSALIW LTFATGERVN FGESSK
//