ID   A0A2G5EG57_AQUCA        Unreviewed;       126 AA.
AC   A0A2G5EG57;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Rab5-interacting protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AQUCO_00900959v1 {ECO:0000313|EMBL:PIA54738.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA54738.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA54738.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the EMC6 family.
CC       {ECO:0000256|ARBA:ARBA00009436}.
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DR   EMBL; KZ305026; PIA54738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5EG57; -.
DR   STRING; 218851.A0A2G5EG57; -.
DR   InParanoid; A0A2G5EG57; -.
DR   OrthoDB; 2998143at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0097250; P:mitochondrial respirasome assembly; IEA:InterPro.
DR   InterPro; IPR029008; EMC6-like.
DR   InterPro; IPR010742; RCAF1.
DR   PANTHER; PTHR12906; PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR12906:SF0; RESPIRASOME COMPLEX ASSEMBLY FACTOR 1; 1.
DR   Pfam; PF07019; EMC6; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        56..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        106..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   126 AA;  14173 MW;  4BFCA5A559B61DB2 CRC64;
     MKSLKSNQKQ KQQQNNDDVS PFNFSKLLDP DASWDKDQLG DVLHWIRQSV GLFCGLLWGS
     IPLVGAIWIV LFLVLSSAIV YGYYAIVLKV DEEDFGGHGA LLQEGLFASL TLFLLAWILV
     YSLVHF
//