ID   A0A2G5EIV5_AQUCA        Unreviewed;       317 AA.
AC   A0A2G5EIV5;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=indole-3-pyruvate monooxygenase {ECO:0000256|ARBA:ARBA00039148};
DE            EC=1.14.13.168 {ECO:0000256|ARBA:ARBA00039148};
GN   ORFNames=AQUCO_00700171v1 {ECO:0000313|EMBL:PIA55669.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA55669.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA55669.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + indole-3-pyruvate + NADPH + O2 = (indol-3-yl)acetate +
CC         CO2 + H2O + NADP(+); Xref=Rhea:RHEA:34331, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:17640, ChEBI:CHEBI:30854, ChEBI:CHEBI:57783,
CC         ChEBI:CHEBI:58349; EC=1.14.13.168;
CC         Evidence={ECO:0000256|ARBA:ARBA00035920};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; KZ305024; PIA55669.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5EIV5; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR43539:SF56; EXPRESSED PROTEIN; 1.
DR   PANTHER; PTHR43539; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220); 1.
DR   Pfam; PF13738; Pyr_redox_3; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
SQ   SEQUENCE   317 AA;  36139 MW;  DC0B78D0D6873673 CRC64;
     MNKELKRVWV PGPVIIGAGP SGLAAGACLK EKGVPSLILE RENCLASLWK LKTYDRLRLH
     LPKKFCELPY MDFPPEFPTY PTKQQFLNYL NDYANMFSIK PIFEEEVRLA EYDSNIGFWF
     VQTNNFEFVC QWLIVATGEN SEPVTPELPQ ISNFRGRILH TSRYKNGYEF EGEKVLVVGC
     GNLGMEISLD LCNSGAQALI SVRNMVHILP REILGLSTFG LSMWLLKWIP LKLVDLFLLL
     SSLFILGDTQ RFGFKRPKIG PLDIKNTIGK TPVLDVGCLA KIRTGKIKVY STSIPSFQKI
     HVYIFFLSIY IYRVKAR
//