ID   A0A2G5ERY2_AQUCA        Unreviewed;       489 AA.
AC   A0A2G5ERY2;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN   ORFNames=AQUCO_00500445v1 {ECO:0000313|EMBL:PIA58505.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA58505.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA58505.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305022; PIA58505.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5ERY2; -.
DR   STRING; 218851.A0A2G5ERY2; -.
DR   InParanoid; A0A2G5ERY2; -.
DR   OrthoDB; 56553at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   CDD; cd20071; SET_SMYD; 1.
DR   Gene3D; 6.10.140.2220; -; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR044237; ATXR2-like.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR002893; Znf_MYND.
DR   PANTHER; PTHR47436; HISTONE-LYSINE N-METHYLTRANSFERASE ATXR2; 1.
DR   PANTHER; PTHR47436:SF1; SET DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00856; SET; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          40..459
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          131..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..156
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  55177 MW;  91E2D0A17D37F23A CRC64;
     MDSSSSSSLI FCQLDKEFSK EISSLLKPPS SKQVQEYFDE LVKTRQCNGL KIKNNGNYGK
     GVYAESDFNE GELVLKDQML VGAQHSSNKV DCLVCSYCFR FIGSIELQIG RKLYLQDLGV
     SARMECATES SDEEDNSLTA DHDDFGQCSS SNSKKKVPLP RETIESVMNG DVELPYSKQF
     PLPSAVSCPG GCEEAYYCSK ICAEADWEFF HSLLCTGKCL GTPSREALLK FIQHADGTND
     IFYLAAKAIS STILRYRKSK AAQVQDKGKH NEVSGNDNSD FSLLLEAWKP ISMGYKRRWW
     DCVALPDDVD YRDEASFREQ IRELAFESLQ LLKEAIFDKE CAPLFSLEIY GHIIGMFELN
     NLDLVVASPV EDYFLYIDDL QNEKKERAER ITRPFLDALG DEYSICCQGS AFFPLQSCMN
     HSCHPNAKAF KREEDRDGQA TIIAVRSIGK EEEITISYID EDLPFKERQA LLADYGFKCS
     CCKCLEEKS
//