ID   A0A2G5EWJ8_AQUCA        Unreviewed;       452 AA.
AC   A0A2G5EWJ8;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=AQUCO_00400760v1 {ECO:0000313|EMBL:PIA60091.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA60091.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA60091.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000256|ARBA:ARBA00007637}.
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DR   EMBL; KZ305021; PIA60091.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5EWJ8; -.
DR   STRING; 218851.A0A2G5EWJ8; -.
DR   InParanoid; A0A2G5EWJ8; -.
DR   OrthoDB; 5484762at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   CDD; cd05255; SQD1_like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR43000:SF10; UDP-SULFOQUINOVOSE SYNTHASE, CHLOROPLASTIC; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          58..346
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   452 AA;  50665 MW;  2246B8AC1D934DFC CRC64;
     MSQSSTFYPT SLTLQTSTFP SKRSRQRGLT VFATALSPSQ SSSVFDHKDT EPSRPKRVMI
     IGGDGYCGWA TALHLSKQNY EVAIVDNLVR RLFDHQLGLD SLTPISSIHN RVRRWKSLTG
     KTIELYIGDI CDFEFLSETF KSFEPDSVVH FGEQRSAPYS MIDRSRAVFT QHNNVIGTLN
     VLFAIKEYRE DCHLVKLGTM GEYGTPNIDI EEGYITINHN GRTDTLPYPK QGSSFYHLSK
     VHDSNNIAFT CKAWGIRATD LNQGVVYGVT TDETEMHEDL CNRFDYDGVF GTALNRFCVQ
     AAVGHPLTVY GKGGQTRGYL DIRDTVQCVE LAIANPAQPG EFRVFNQFTE QFSVNELASL
     VTKVGKKLGL DVKTISVPNP RVEAEEHYYN AKHTKLVELG LKPHLLSDSL LDSVLNNAIR
     FKDRVDTKQI MPSVSWKKIG AKPKTVSAYP NN
//