ID A0A2G5EYG6_AQUCA Unreviewed; 360 AA.
AC A0A2G5EYG6;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Fatty acid desaturase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AQUCO_00300369v1 {ECO:0000313|EMBL:PIA60798.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA60798.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA60798.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; polyunsaturated fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005105}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; KZ305020; PIA60798.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5EYG6; -.
DR STRING; 218851.A0A2G5EYG6; -.
DR InParanoid; A0A2G5EYG6; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF13; DELTA(12)-FATTY-ACID DESATURASE; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..65
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 81..322
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 360 AA; 41651 MW; 2D6074738DD59806 CRC64;
MNACGHISDT TESYKKNVNH QRAPCMKPPF SLSQLKKAIP PHCFQRSVIC SFSYVVHDLI
IAFMLYCVAT TCIPLLPQCI SWMAWSIYWV VQGCILTGLW VIGHECGHHA FSDYQWLDDT
IGLILHSFLL VPYFSWKYSH RRHHSNIGSL EHDEVFVPKT KSKVPQYFKY FNNFPGRVLT
LAITLLLGWP LYLSFNASGH YYDRFACHFD LIVQFSPILA AANGFCYLIC VYGIPLLVVN
AFLVLITYLQ HTHPSLPHYN SSEWDWLRGA LITVDRDYGV LNKVFHNITD THVAHHLFAS
IPHYHAMEAT KAIKPILRDY YQYDATPFLK AMWRETKECI YVESDEGTTS KGVFWYSNKF
//
