ID A0A2G5F745_AQUCA Unreviewed; 523 AA.
AC A0A2G5F745;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=AQUCO_00201232v1 {ECO:0000313|EMBL:PIA63746.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA63746.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA63746.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; KZ305019; PIA63746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5F745; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF52; U-BOX DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF00514; Arm; 2.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 6.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT DOMAIN 143..217
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 284..326
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 325..367
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 523 AA; 57637 MW; 3C9FFC617223AA6B CRC64;
MKDEAGKKLM FEFQTLSSHL EKTLGSLPYD FFEISDEVRE QVELVRAQLK RATERYRHRN
PVVLSRALSQ PIGEELDYQE LGNICNIGQY LQPKLDKVPN INSKRRHLFS TPGFCELNGA
DSIKAAELAD KNGDDTKKSD SVTIPDDFRC PISLELMRDP VIVATGQTYE RSCIQRWIDC
GNKTCPKTQQ QLLNFSLTPN YVLRSLISQW CEKHNIEQPK GSTNGRLRKS DGSFQEVSGD
IATINALVHK LSSRSVEERR NAATEIRSLS KRSTDNRILI AEAGAIPILV NLLTSEDLKT
QENVVTSILN LSIYENNKSL IMLAGAVPSI VQVLRMGSME ARENAAATLF SLSLLDENKI
TIGASGAIAA LVELLQNGSL RGKKDAATAL FNLCIYQGNK GRAVRAGILL PLMKMLTDTS
YSMVDEALTI LSVLASHQEG KTAIAKASTI PVLIDLLRTG LPRNKENAAA ILLALCKKDA
DNLACIGRLG AIIPLTELAK SGTERAKRKA TSLLEHLRKL QQL
//
