ID A0A2G5F7N0_AQUCA Unreviewed; 961 AA.
AC A0A2G5F7N0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA-directed DNA polymerase family A palm domain-containing protein {ECO:0000259|SMART:SM00482};
GN ORFNames=AQUCO_00201341v1 {ECO:0000313|EMBL:PIA63950.1};
OS Aquilegia coerulea (Rocky mountain columbine).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC Aquilegia.
OX NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA63950.1, ECO:0000313|Proteomes:UP000230069};
RN [1] {ECO:0000313|EMBL:PIA63950.1, ECO:0000313|Proteomes:UP000230069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT "WGS assembly of Aquilegia coerulea Goldsmith.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KZ305019; PIA63950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5F7N0; -.
DR Proteomes; UP000230069; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR CDD; cd08640; DNA_pol_A_plastid_like; 1.
DR CDD; cd06139; DNA_polA_I_Ecoli_like_exo; 1.
DR Gene3D; 3.30.70.370; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR001098; DNA-dir_DNA_pol_A_palm_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR002298; DNA_polymerase_A.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10133; DNA POLYMERASE I; 1.
DR PANTHER; PTHR10133:SF27; DNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00476; DNA_pol_A; 2.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR PRINTS; PR00868; DNAPOLI.
DR SMART; SM00482; POLAc; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT DOMAIN 691..921
FT /note="DNA-directed DNA polymerase family A palm"
FT /evidence="ECO:0000259|SMART:SM00482"
FT REGION 126..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 961 AA; 107930 MW; CFEB174CF9FEFFB8 CRC64;
MPHVLHYDPA NIDHQDRKNT STLDSWVEAS EKLKQDKFNE NEKRRLLELK TSHATKDSNN
NSKGLQEDGS YYLGQSFSDS SSCSLKLDTA QVNGQSRPIC QSEFQNVRSE ELISVNGRGK
GTFHLIDDTR EINSPRKENS NKDVHSNGSS RRHLETAERN SASKGVAKFD HTQKPKAIST
DHRKNLSRIY DEVVVVNSIS EAKKVVRLLT TEYRDLVHAC DTEVSNIDVK QETPVDHGEI
ICFSIYSGQT ADYGKGKSCI WVDVLDGGGR ELLMEFAPFF EDPSIKKVYH NYSFDSHVIE
NYGIKISGFH ADTMHMARLW DSARRTEGGY SLEALTSDSR VMNEAQSCRN RELIGKISMK
TIFGKQKLKR DGSEGKLTII PPVEEIQREE PILWTCYSAL DSMSTLQLFE SLLKKLEKME
WVSNGKLEGS MFQFYEKYWR PFGELLVKME TEGMLVNCAY LAEIQKVATR EQQIASDRFR
KWAARYCPDA MHMNVGSDAQ LRQLFFGGTL NSKDPNEALP LSRSFKVPNT DNVIEEGKKQ
PSKFRDITLC SLGVTMETEI YTASGWPSVS GDALKTLAGK VSSEYDWIDD EDTSTDQISE
TEVDDSYGTA YEAFGREKEG KEACHAIAAL CEVCSIDSLL SNFILPLQSN NISGKNGRIH
CSLNINTETG RLSARRPNLQ NQPALEKDRY KIRQAFIAAP GNSLIVADYG QLELRILAHL
ANCKSMKDAF KAGGDFHSRT AMNMYSHIRE AVEKQEVLLE WHPQSSDDKP PVPLLKDAFG
SERRKAKMLN FSIAYGKTPV GLARDWKVSV KEAKATVNLW YSDRKEVLYW QKERKEEANL
KGSVKTLLGR TRSFPSLRGA SNSHKGHIER AAINTPVQGS AADVAMCAML EISKNARLRE
LGWKLLLQVH DEVILEGPAE SAEVAKAVVV ECMSKPFDGT NILSVDLAVD AKCAQNWYAA
K
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