ID   A0A2G5F889_AQUCA        Unreviewed;      1028 AA.
AC   A0A2G5F889;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIA64224.1};
GN   ORFNames=AQUCO_00100009v1 {ECO:0000313|EMBL:PIA64224.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA64224.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA64224.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305018; PIA64224.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5F889; -.
DR   STRING; 218851.A0A2G5F889; -.
DR   InParanoid; A0A2G5F889; -.
DR   OrthoDB; 990669at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155:SF1156; DISEASE RESISTANCE PROTEIN RGA3; 1.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00369; LRR_TYP; 2.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          6..99
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          182..400
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1028 AA;  117303 MW;  4E0AA32AC2B5AC5D CRC64;
     MAEALVSAVL EHLVTPAIEQ VTEEVRLVRS VGNEIKSLVE ELAKIKSLLE DAEKKQIHDK
     SVKAWFEELK GIAYDVDDVL DEWHTRILQQ IATNDDSSTS KQNKKKVFAC FSSPFNRSQP
     VLVRYRIAHR IKDLRQQLDT NAKIIPGLQL IASQASHHHE DLPSRQIISS FVDPSKIHGR
     DHEKAEIMSW LRSQQEAKVS VMSVVGTPGF GKTALVQLVF HQENDKNTFD PTMWVSVSEP
     VDLQRLAKEI IESATGKKPE VDGLEALLRH LSDTVKGKMF MLILDDVWPK YLEHWWEQLK
     SSLDSGAQGS KIIITTRYQK VADVVESSCI ILLRELQYEA CWSLFKRIAF SRRSANNHHN
     LEGIGEEIVK KCKGVPLAIK TIASLMQYKQ TIHEWESVRD SDVWEHVGEK LLPSLLLSYH
     AFPSYLKQCF MYCAVIPKDT LMKKDTLVKL WMAQGFLGSN GGKELETVGG AYFDELAMRS
     FFQDFEKDGD GSVVSCKIHD LVHDFAQSLT ITECCVIQMN DKETCNSKVR HLTAPDTENP
     SISKVQKNLR TLITLSLSDS TDVCKLFRQL TCLRTLDLSG SHFKELPKEV ELLLHLRYLD
     LSRTKLTELP ESLCKLYNLQ TLKLDYCFDL PKLPNGIGEL SNLRHIENKE TYELKYFPKG
     IERLSCLRTL NKFVVSGATG GCRIGELGNL IHLGGDLEIR GLWQVENMIE AKQAGLQEKK
     NLDSLLLDFD GGEFRSAEDR EKMEGVLKGL QPHNNLKTLE IYEYPGLTVN LEICIHLRHL
     NFSYCRNITS LPADLGKLQF LESLDVDYAP EIKDVSFQLL KISGNGDSSS LELFPKLQFL
     KLSNLRKWEE EEEENEKIDR FSIMPCLLEL EIVFCPKLKV LPHYMMFSQT LRKLRIHNCP
     RLSGMKPCLP SLLEELRLWG DVGVLSSSLM PIIHNNNNSN NSYPNLKSVI IDFSKNSSLP
     QGLNQFTSLQ KLHLSYCESL DFKPEEEFRH LHTLPTLTIT IYNCPLLKER SSRDDWANLS
     NFPKIIFQ
//