ID   A0A2G5F8X8_AQUCA        Unreviewed;      1069 AA.
AC   A0A2G5F8X8;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Disease resistance protein RGA3 {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=AQUCO_00100141v1 {ECO:0000313|EMBL:PIA64451.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA64451.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA64451.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KZ305018; PIA64451.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5F8X8; -.
DR   STRING; 218851.A0A2G5F8X8; -.
DR   InParanoid; A0A2G5F8X8; -.
DR   OrthoDB; 1122392at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155:SF1156; DISEASE RESISTANCE PROTEIN RGA3; 1.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50270; NGF_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069}.
FT   DOMAIN          12..90
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          188..387
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PIA64451.1"
SQ   SEQUENCE   1069 AA;  122529 MW;  2DF09E03BAFB079F CRC64;
     QVYNIRMAGA LVSTVLEQLH SLIMEVEVEV EIDVKKVVNR LIKSLIIVQG VLEDAENKQM
     KNEAVRNWLE ELKDVLYETD DVVDEWITKR RPISQIRGTE TVVVDELGIG KKVLSSYLYS
     CFCFNPVIVG DFRHKILKIE ERMDMIVRWK YRFNLNPHRS QRNEIILGRD LDKEVIVSRL
     LSESSHGEMN FQVISIIGTG GFGKTTLAKL VFNEVSEFFD YRIWVCVSDP FDLKEIANAI
     IREAKQYVPL IVGWEALHQC LCESLKGKRF LLVLDDVWNI HSEEWISLKH PLNGGASGSR
     VIVTSRTNIV AKVMDSSYIH WLGQLSTEDC WLLFKNLAFC GRQAEENEMF DDIGKEIAKK
     CKGVPLAVKI LGSVMYFERT IQDWRNILVT DIWDTLEFGS GFQSSLILSY HALPPPLKQC
     FLYCAIFPKG KVIERDSLIK LWMAQGFLDC DGRRDLEIIG GEFFVNLAMR SLFQDLEVDF
     DGNITSCKMH DLVQDFAQFL TQTECSIRDM EIDRQEYCEC IITLWRKNLR TLMAPSEYGK
     STIPVKLFYE LARLRALDFS DCDLEELPLE VGRLLHLRYL DLSSTKLRVL PETICHLKNL
     QTLKLNRCRN LIELPKEIGK VSTLRHLEIK GTKDLDYMPR GIGKLSFLRT LDKFIVGGKS
     DGCEIGELHL LNHIQGKLKI MGLGQVSVWN EAVGAELKKK QYLRELTLDF GNFGESDVGM
     MENVLENLEP PEYLYELVIN GYQGCHFPCW IMSRSISTNS LRLLVLRNCE RCTHLPALGK
     FPSLEKLVIS GMSQVKYIGH EFFGLADVGT GEEEALYTQV VFPKLRKLKF YNMEEWEEWA
     SPFHSNRVTM PCLRDLTLVG CPKLRNSLNL LGLKSLEILH LHGLDSMAQW EDGEVPGKGG
     DINSCLREVV IAFCPKLKLV PRYMFSHTLR HLWITQCPEL RGMQPCIPPL LESLVFRGDL
     GVLSESLPLN QNSDYSNYPE LKSFTISCSP HPSLPLGFSQ FTAIQTLKFL SCESLDFELS
     ELKHLNRLKE LHIYECPILN KRFAEGKDWS ILSYVPKISI NCCQISEDN
//