ID   A0A2G5F956_AQUCA        Unreviewed;       463 AA.
AC   A0A2G5F956;
DT   31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT   31-JAN-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN   ORFNames=AQUCO_00100189v1 {ECO:0000313|EMBL:PIA64533.1};
OS   Aquilegia coerulea (Rocky mountain columbine).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ranunculales; Ranunculaceae; Thalictroideae;
OC   Aquilegia.
OX   NCBI_TaxID=218851 {ECO:0000313|EMBL:PIA64533.1, ECO:0000313|Proteomes:UP000230069};
RN   [1] {ECO:0000313|EMBL:PIA64533.1, ECO:0000313|Proteomes:UP000230069}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Goldsmith {ECO:0000313|Proteomes:UP000230069};
RA   Hodges S., Kramer E., Nordborg M., Tomkins J., Borevitz J., Derieg N.,
RA   Yan J., Mihaltcheva S., Hayes R.D., Rokhsar D.;
RT   "WGS assembly of Aquilegia coerulea Goldsmith.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KZ305018; PIA64533.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2G5F956; -.
DR   STRING; 218851.A0A2G5F956; -.
DR   InParanoid; A0A2G5F956; -.
DR   OrthoDB; 1220854at2759; -.
DR   Proteomes; UP000230069; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR045843; IND-like.
DR   PANTHER; PTHR45914:SF12; TRANSCRIPTION FACTOR BHLH87; 1.
DR   PANTHER; PTHR45914; TRANSCRIPTION FACTOR HEC3-RELATED; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000230069};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          365..414
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   REGION          204..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          282..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..253
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..326
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  51084 MW;  4ACF5F1AED40867E CRC64;
     MDRLRWDSLS SCIQGRQWSY HQPEIKENPR GHSDDSSIVA GNADLVDNLL NPGHDIYGNK
     SCNLVRENGM AVQQLAPASD SLYGASTLDI SQRQAAPKMA SNTGLVKSGC GTTWGEGLTS
     GTPLINRLYS TSPISSLMPD FDNKMPVTNG VEGDTVAADS FESLDCLLSA TNSNTDTSVE
     DDGISMLFSD CRNLWNFNSN SAISSGESEN NGAKDDDNEA CPQVSKPNEG SRCYTNPSFN
     HVSNSPDTWP SSSSKRNREQ EEIKMPENYR CFELFQTDSS TNTEGGFQLI SENPSKAKKP
     RLEKQQKTSN INFQHPNSSV SSSLDEPDNE AIAQVKEMIY RAAVFRPVSL DLDVVEKPKR
     KNVRISSDPQ TVAARQRRER ISERIRILQR LVPGGNKMDT ASMLDEAANY LKFLRSQVKA
     LETLGHKLGS VSSSTSTNLS FPSLPFNHNF TMQPFFPFQN PNP
//