ID A0A2G5I3W3_CERBT Unreviewed; 539 AA.
AC A0A2G5I3W3;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase {ECO:0000313|EMBL:PIA99448.1};
GN ORFNames=CB0940_03068 {ECO:0000313|EMBL:PIA99448.1};
OS Cercospora beticola (Sugarbeet leaf spot fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Cercospora.
OX NCBI_TaxID=122368 {ECO:0000313|EMBL:PIA99448.1, ECO:0000313|Proteomes:UP000230605};
RN [1] {ECO:0000313|EMBL:PIA99448.1, ECO:0000313|Proteomes:UP000230605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=09-40 {ECO:0000313|EMBL:PIA99448.1,
RC ECO:0000313|Proteomes:UP000230605};
RA De Jonge R., Ebert M.K., Suttle J.C., Jurick Ii W.M., Secor G.A.,
RA Thomma B.P., Van De Peer Y., Bolton M.D.;
RT "The cercosporin biosynthetic gene cluster was horizontally transferred to
RT several fungal lineages and shown to be expanded in Cercospora beticola
RT based on microsynteny with recipient genomes.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIA99448.1}.
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DR EMBL; LKMD01000101; PIA99448.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5I3W3; -.
DR OrthoDB; 2013830at2759; -.
DR Proteomes; UP000230605; Chromosome 3.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR PANTHER; PTHR10606:SF39; 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:PIA99448.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000313|EMBL:PIA99448.1}.
FT DOMAIN 45..264
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
FT REGION 481..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 60731 MW; CA1DDACB0EBBD22B CRC64;
MDTLLTADVA GSAPNFRRRS STYVDAIHDL PEKASMAPAQ LYSTESGRLF HSGRIVIATV
GLPARGKTHI SVALARYLRW LGVKTHIFHL GDYRRAFVGA KGEVPEDYFH INASTSSVLL
RNKILKRCRE DIFNFLNHEN GQIAIYDAVN PLATGRRALA KEFEKHGVQT MFIECTCSDP
RIIEENVRAV KISSPDYVGW KPEDAVQDYL RRINARIPDY EGVEERDLHY VKMINAGERV
IVNSCAFGYL SQRIVFYLLN LHIKSRQMYF VRAGTTREEE TFKGDASLSA EGWDYAKRMT
DAIVAHRETE REMLIKNGAP ESTASKPLQV WTSTRKRTVE TATFFEKLGY RVRQRSQMSQ
LNPGVCEKLS ERRIRELFPE EVDKHEQDPY HHRYPRAESY HDLAVRLEPI ILELEREQND
LLIIAHESVL RVLYGYLMAC SAHDIPTLEF PRDEIIEVIP ASYNNSAKRI HIDGLPPSMI
PSSPQDIQIP VPPSGAVSPL NGGLGTPAGI ATPETAGRES GALPIRPSAT LGETLQPRG
//
