ID A0A2G5IXN0_9ACTN Unreviewed; 735 AA.
AC A0A2G5IXN0;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Isoquinoline 1-oxidoreductase {ECO:0000313|EMBL:PIB09738.1};
GN ORFNames=B1C81_10095 {ECO:0000313|EMBL:PIB09738.1};
OS Streptomyces sp. HG99.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1958787 {ECO:0000313|EMBL:PIB09738.1, ECO:0000313|Proteomes:UP000231274};
RN [1] {ECO:0000313|EMBL:PIB09738.1, ECO:0000313|Proteomes:UP000231274}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HG99 {ECO:0000313|EMBL:PIB09738.1,
RC ECO:0000313|Proteomes:UP000231274};
RA Li Y.;
RT "Diversity and bioprospecting of biosynthetic gene clusters of culturable
RT actinobacteria from Tibetan Plateau, China.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIB09738.1}.
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DR EMBL; MVDM01000004; PIB09738.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5IXN0; -.
DR Proteomes; UP000231274; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.90.1170.50; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; 1.
DR Gene3D; 3.30.365.10; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain; 4.
DR InterPro; IPR000674; Ald_Oxase/Xan_DH_a/b.
DR InterPro; IPR008274; AldOxase/xan_DH_MoCoBD1.
DR InterPro; IPR046867; AldOxase/xan_DH_MoCoBD2.
DR InterPro; IPR037165; AldOxase/xan_DH_Mopterin-bd_sf.
DR InterPro; IPR012368; OxRdtase_Mopterin-bd_su_IorB.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR47495; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR47495:SF1; BLL3820 PROTEIN; 1.
DR Pfam; PF02738; MoCoBD_1; 1.
DR Pfam; PF20256; MoCoBD_2; 2.
DR PIRSF; PIRSF036389; IOR_B; 1.
DR SMART; SM01008; Ald_Xan_dh_C; 1.
DR SUPFAM; SSF56003; Molybdenum cofactor-binding domain; 2.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000231274}.
FT DOMAIN 223..302
FT /note="Aldehyde oxidase/xanthine dehydrogenase a/b
FT hammerhead"
FT /evidence="ECO:0000259|SMART:SM01008"
SQ SEQUENCE 735 AA; 77982 MW; 6C52B37934DCAD6B CRC64;
MTGHARRRFL TYLVAAPTLA VATRIGLDGY APGTAEAAIP TPPAPADLVD LGDLLILAGQ
PTAGMLVLSV DEDGVVHFRL PREEVGQGLT TAVAMLVAEE LDVPLDRVRV QLEDARPELL
FNQLTGSSNS IRSLYDPVRH TAAAARARMV GAAAKQWGLN AGDVTVRQGV VTAPDGRTAS
YGTLSAAAAS HDLGSLLVTP KKESEHTLVG TPTSRIDARA LVTGRQAYTL DLDVPGAKPC
MVRRPPTING TVKAVNNETV VRAMPGVLDV VAIDTGVAVV ADTFGQALDA KEALDVTWGG
GTVDTLSDDE IRAKLKAATP SLDPLGLLVS KVDAEFDFAF ASHAPMETNS AVADVRADGA
EIWSGMKSPI AAQAAIAAAV GLPVGKVKVH VVQSGGSFGR RLFYDAALEA AVVSKKSGRP
VRLMWSRIDD MRHGRMRPAT HHRIRATYAL GQVLTFVHQV AAVETDFRHG LGDAITAAAA
SLPTGLGNAT FAQTLFLTTV KSPYNFGVTT QALTEVPLKM HTGSWRSVYS ANTRGAEEIV
VDELAAALRR DPVSFRRSFL KNERQRAVLD KVAQEGDWGR TMPAGWAQGV GFHEEYMSCT
ACLVEIDATD PKRPRVTKAV IAADVGRPVN PRGLEAQLLG GLTDAISTTL RAGLHIDKGL
PLEGSYSQFH YARQKDSPRD VRIFVLPTDH EPGGAGELGV PAAVGAIANA YARATGTRPR
SFPVNFDVDF TPFPR
//
