ID A0A2G5J2Z8_9ACTN Unreviewed; 539 AA.
AC A0A2G5J2Z8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:PIB11152.1};
GN ORFNames=B1C81_04725 {ECO:0000313|EMBL:PIB11152.1};
OS Streptomyces sp. HG99.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1958787 {ECO:0000313|EMBL:PIB11152.1, ECO:0000313|Proteomes:UP000231274};
RN [1] {ECO:0000313|EMBL:PIB11152.1, ECO:0000313|Proteomes:UP000231274}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HG99 {ECO:0000313|EMBL:PIB11152.1,
RC ECO:0000313|Proteomes:UP000231274};
RA Li Y.;
RT "Diversity and bioprospecting of biosynthetic gene clusters of culturable
RT actinobacteria from Tibetan Plateau, China.";
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIB11152.1}.
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DR EMBL; MVDM01000002; PIB11152.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2G5J2Z8; -.
DR Proteomes; UP000231274; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR PANTHER; PTHR11780:SF10; NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11780; NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13459; Fer4_15; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000231274};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 325..369
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
FT REGION 513..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 56045 MW; FFCF67680341E572 CRC64;
MNEALPDVPE VRVVGLPQLT SGFDLVERLD LPMHLKVHGP LEPMGGEQLA SLAEAISLKG
RGGAGFPFAK KLRSVAETAI KKGIRPVVVV NGSEDEPACR KDTVLINRAP HLILDGALLA
AEAMGARTLV VGVTRESTQR SMEAALAERG LSNRRGSAVR ARVQRNPVRM VTGAAASLIR
SIDGGPAIPP GRKISASQSG VGGAPTLLSN AETFAQLAIA ARMGPDRYRN TGLYDEPGTV
MLTVSGAVAR PMVIEVPTGV PLRYVLQLAG APPSPQGVLT GGYHGKWLDA ATVDEAIVSR
NSLDAVGGAL GAGAVLPISQ QTCPLGESLR VAQWLAEESA GQCGPCYLGL PAAARGLEDI
LNGGGPAALE AVKQVAKAVK RRGACSHPDG SAMFIESTIK AFTDDLAAHV LGNGCGRPVE
GVLPLFEGGQ VPTGVPGGQG QQETGPSRQK IYVDWTLCRG HGLCADILPE VFELGADGFP
TVAQAQVPRY AEAKAMRAVR RCPALALRIE EDTRSSAPAR NNLPVLSQGR GRRALGSGR
//
